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Table 1 Differential expression of genes between Parp-1+/+ and Parp-1-/- ES cells, livers, and EFs

From: Loss of Parp-1 affects gene expression profile in a genome-wide manner in ES cells and liver cells

 

No. of genes

  

Parp-1-/- <Parp-1+/+

Parp-1-/- > Parp-1+/+

p-value cut offa

Total

Total

2-fold or greater

Total

2-fold or greater

ES cells c

     

Totalb

9,907

5,464

1,283

4,349

1,406

p < 0.05b

2,273

1,609

626

664

324

p < 0.01b

928

684

259

244

120

Livers d

     

Totalb

12,353

7,138

1,184

4,860

1,038

p < 0.05b

1,616

1,190

253

426

158

p < 0.01b

641

515

100

126

43

EFs e

     

Total

12,359

5,042

707

7,317

501

p < 0.05

996

390

216

606

205

  1. a Analyzed by One-Way ANOVA (non-parametric test known as Wilcoxon-Mann-Whitney test)
  2. b These genes were presented in Fig. 1 (A)-(F).
  3. c Parp-1+/+ ES cell clone, J1, and Parp-1-/- ES cell clones, 210-58 and 226-47, were used.
  4. d Two mice were used for each genotype.
  5. e Three EFs obtained from three embryos were analyzed as triplicate experiments.
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BMC Genomics

ISSN: 1471-2164

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