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Table 2 p68 and p72 frequency analysis of non-overlapping hits (all over 30% and selected below 30%).

From: Identification of novel pathway partners of p68 and p72 RNA helicases through Oncomine meta-analysis

p68 selected genes with no p72 overlap

Gene

% Overlap

Function

Gene Name

FXR1

42%

RNA-binding/Unknown

fragile X mental retardation, autosomal homolog 1

HNRPK

37%

Transcription/Translation/Signaling

heterogeneous nuclear ribonucleoprotein K

NAP1L1

32%

Transcription

nucleosome assembly protein 1-like 1

JMJD1C

32%

Transcription

jumonji domain containing protein 1C (Thyroid receptor interacting protein 8)

SFRS11

32%

Splicing

splicing factor, arginine/serine-rich 11

MAPRE1

37%

Cytoskeleton

microtubule-associated protein, RP/EB family, member 1

ACTG2

32%

Cytoskeleton

actin, gamma 2, smooth muscle, enteric

PTPN11

32%

Signal Transduction

protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)

JAK1

32%

Signal Transduction

janus kinase 1 (a protein tyrosine kinase)

ARF3

32%

Vesicular Trafficking

ADP-ribosylation factor 3

ANXA7

32%

ER-calcium mobilization

annexin A7 (Annexin VII) (Synexin)

COX7A2L

32%

Metabolism

cytochrome c oxidase subunit VIIa polypeptide 2 like

C6orf55

32%

Anti-metastatic protein

protein C6orf55 (Dopamine responsive protein DRG-1) (My012 protein)

LAPTM4A

32%

compartmentalization of amphipathic solutes

lysosomal-associated protein transmembrane 4 alpha

ZNF9

32%

?

zinc finger protein 9 (a cellular retroviral nucleic acid binding protein)

TDE1

32%

?

tumor differentially expressed 1

SYPL

32%

?

synaptophysin-like 1

NUCKS

32%

?

nuclear, casein kinase and cyclin-dependant kinase substrate

ELK3

26%

Transcription

ELK3, ETS-domain protein (SRF accessory protein 2)

THRAP1

21%

Transcription

thyroid hormone receptor associated protein 1

RBBP4

21%

Transcription

retinoblastoma binding protein 4 (chromatin assembly factor/CAF-1 p48 subunit)

ERBP

21%

Transcription

estrogen receptor binding protein

RARA

16%

Transcription

retinoic acid receptor, alpha

HDAC2

16%

Transcription

histone deacetylase 2

SNRPB

26%

Splicing

small nuclear ribonucleoprotein polypeptides B and B1

TAPBP

26%

ER chaperone/Protein folding

TAP binding protein (tapasin)

CALR

21%

ER chaperone/Protein folding

calreticulin

CANX

16%

ER Chaperone/Protein folding

calnexin

RAB1A

26%

ER-golgi Transport

RAB1A, member RAS oncogene family

RAB11B

21%

Membrane recycling

RAB11B, member RAS oncogene family

UCHL1

21%

Ubiquitin

ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

PSMA2

21%

Proteolysis

proteasome (prosome, macropain) subunit, alpha type, 2

PRKWNK1

21%

Proteolysis

proteasome (prosome, macropain) 26S subunit, non-ATPase, 1

SUMO2

16%

SUMO pathway

small ubiquitin-like modifier, 2

CDC42

21%

Cell-cycle

cell division cycle 42 (GTP binding protein, 25kDa)

CDC40

21%

Cell-cycle

cell division cycle 40 homolog (yeast) [pre-mRNA splicing factor 17]

CDC10

26%

Cytokinesis?

septin-7 (CDC10 protein homolog)

LITAF

26%

p53-induced Apoptosis

lipopolysaccharide-induced TNF factor (p53-induced protein 7)

EIF3S10

26%

Translation

eukaryotic translation initiation factor 3, subunit 10 theta, 150/170 kDa

p72 selected genes with no p68 overlap

Gene

% Overlap

Function

Gene Name

TTC3

32%

?

tetratricopeptide repeat domain 3

HMGN4

26%

Transcription

high mobility group nucleosomal binding domain 4

CTBP1

21%

Transcription/corepressor

C-terminal binding protein 1

MTA1

21%

Transcription/ER-alpha repressor

metastasis associated 1

HDAC7A

16%

Transcription

histone deacetylase 7A

NONO

16%

Splicing/Transcription

non-POU domain containing, octamer-binding (p54nrb)

SFRS3

16%

Splicing

splicing factor, arginine/serine-rich 3

MAP2K3

26%

Signal Transduction

mitogen-activated protein kinase kinase 3

ERBB3

16%

Signal Transduction

receptor protein-tyrosine kinase erbB-3

CSK

16%

Signal Transduction

c-src tyrosine kinase

CALM2

16%

Signal Transduction

calmodulin 2 (phosphorylase kinase, delta)

RPS6

21%

Ribosome

40S ribosomal protein S6

RPS15A

21%

Ribosome

40S ribosomal protein S15a

MRPS6

26%

Mitochondrial Ribosome Protein

mitochondrial ribosomal protein S6

PABPC1

26%

Translation

poly(A) binding protein, cytoplasmic 1

EIF5

21%

Translation

eukaryotic translation initiation factor 5

EDD

26%

ubiquitin E3 Ligase

ubiquitin--protein ligase EDD

ARPC3

26%

Cytoskeleton

actin related protein 2/3 complex, subunit 3,21 kDa

WSB1

21%

?

WD repeat and SOCS box-containing 1

GARNL1

21%

?

GTPase activating RANGAP domain-like 1

?-Genes with unknown function. Genes with > 30% frequency overlap are in bold.

  1. All coexpressed but non-overlapping gene products for p68 and p72 over 30% frequency are shown (and are in bold). Selected coexpressed gene products below 30% are shown and were chosen based on interest and common ontology groups.