Chicken – human/mouse orthologs. (A) The number of identified predicted proteins that had either human or mouse 1:1 orthologs. (B) Distribution of orthologs identified by different orthology prediction methods. The 4 most commonly used ortholog prediction tools are Homologene, Ensembl, InParanoid and Treefam. Human/mouse orthologs were identified for 77% of the identified chicken proteins (see additional file 3).