Figure 5

Biomarker discovery. The goal of this example was to retrieve genes expressed only in pancreatic cancer, not expressed in chronic pancreatitis and present in plasma. 1. Filter: the query is restricted by clicking on the "Filters" node on the left, expanding the filter section "GENES DIFFERENTIALLY EXPRESSED IN:" and selecting for genes differentially expressed in "Pancreatic adenocarcinoma (PDAC) vs normal pancreas NP (bulk tissue)" as well as "Pancreatic adenocarcinoma (PDAC) vs chronic pancreatitis (bulk tissue)" and expanding the filter section "GENES EXPRESSED IN:" and selecting for genes expressed in "Plasma". 2. Attributes: selected by clicking on the "Attributes" node on the left, choosing the "General Gene Features" attribute page, expanding the attribute section "PANCREATIC EXPRESSION" to remove "Gene Symbol", "Differential Expression Analysis" and "Direction of Regulation" default options, expanding the attribute section "GENE" and selecting "Description" under "Ensembl Attributes". 3. Results: Clicking the "Count" button in the tool bar returns 37 genes satisfying the filters criteria. Clicking the "Results" button on the toolbar will retrieve a result table. Checking the "Unique results only" will display only the unique rows of the result table.