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Table 1 DNA-binding TF-encoding genes in human, mouse and fugu genomes. The TFs were classified based on their DNA-binding domains using a classification scheme adapted from Messina et al. [1]

From: TFCONES: A database of vertebrate transcription factor-encoding genes and their associated conserved noncoding elements

TF family Human Mouse Fugu
AP-2 5 5 6
ARID 11 9 15
Beta-scaffold – CCAAT 8 8 9
Beta-scaffold – MADS 5 5 9
Beta-scaffold – p53 3 3 3
Beta-scaffold – RUNT 3 3 5
Beta-scaffold – Others 28 28 31
BHLH 96 94 134
BZIP 69 65 83
Dwarfin 8 8 13
E2F 11 9 11
Forkhead 40 35 60
GCM 2 2 2
Heat shock factor 7 4 10
High mobility group box 35 39 56
Homeobox 221 199 282
Nuclear hormone receptor 49 49 69
Paired box 9 9 14
RFX 6 6 7
T-box 16 15 19
TEA 4 4 5
Trp cluster – Ets 29 29 31
Trp cluster – IRF 9 9 15
Trp cluster – Myb 11 11 13
ZnF-C2H2 472 290 254
ZnF-C3H 6 4 7
ZnF-DM 9 7 6
ZnF-GATA 10 10 12
ZnF-Others 61 55 73
Others (e.g., SAND, RBPSUH) 84 72 74
Total 1,327 1,086 1,328