Table 2 Functional Classification of Genes Differentially Expressed in Stat3Δ/Δ mice
GO Classification of Genes Up-regulated in Stat3Δ/Δ mice | |||
|---|---|---|---|
Term | Count | % | PValue |
Biopolymer modification | 115 | 13.94 | 7.30E-13 |
Cellular protein metabolism | 164 | 19.88 | 5.83E-10 |
Protein transport | 52 | 6.30 | 2.49E-07 |
Phosphate metabolism | 62 | 7.52 | 3.31E-07 |
Chemotaxis | 17 | 2.06 | 1.38E-06 |
Protein kinase cascade | 24 | 2.91 | 6.83E-06 |
Apoptosis | 40 | 4.85 | 1.69E-05 |
Regulation of apoptosis | 29 | 3.52 | 4.93E-05 |
Positive regulation of cellular metabolism | 25 | 3.03 | 9.95E-05 |
Cell migration | 19 | 2.30 | 2.26E-03 |
Transcription | 106 | 12.85 | 2.64E-03 |
GO Classification of Genes Down-regulated in Stat3Δ/Δ mice | |||
Term | Count | % | PValue |
Cellular lipid metabolism | 33 | 9.97 | 3.60E-13 |
Lipid biosynthesis | 21 | 6.34 | 3.59E-11 |
Sterol metabolism | 10 | 3.02 | 2.96E-07 |
Fatty acid metabolism | 14 | 4.23 | 5.35E-07 |
Steroid metabolism | 12 | 3.63 | 6.83E-06 |
Carboxylic acid metabolism | 18 | 5.44 | 5.84E-04 |
Coenzyme metabolism | 10 | 3.02 | 2.51E-03 |
Cellular carbohydrate metabolism | 12 | 3.63 | 3.98E-03 |
Electron transport | 14 | 4.23 | 2.64E-02 |
Phosphate metabolism | 21 | 6.34 | 3.27E-02 |