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Table 4 Enriched Pathways In Genes Differentially Expressed in Stat3Δ/Δ mice

From: Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells

Term

Count

%

P-Value

Jak-Stat Signaling Pathway

38

3.26

7.56E-09

Apoptosis

24

2.06

5.04E-06

Cytokine-Cytokine Receptor Interaction

43

3.69

2.59E-05

Insulin Signaling Pathway

28

2.40

5.53E-05

Mapk Signaling Pathway

45

3.86

8.51E-05

Focal Adhesion

37

3.17

1.55E-04

Wnt Signaling Pathway

28

2.40

1.68E-04

  1. Overrepresented pathways were identified by comparison the overlap of differentially expressed genes and all genes in MOE430 mouse genome (reference) with the known KEGG pathways. A pathway is considered to be over-represented when a probability P-Value ≤ 0.01 and gene frequency (genes in the pathway/total number of differentially expressed genes) ≥ 2%.