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Table 5 Embryonic stem cell marker genes expressed in hES SA02 cell line, as detected by the NeuroStem Chip analysis

From: "NeuroStem Chip": a novel highly specialized tool to study neural differentiation pathways in human stem cells

N

Gene indexa

Gene name

Log2 Ratio

S.E.M (%)

1.

Hesx1

Homeo box expressed in ES cells 1

4.11

5.76

2.

Grem1

Gremlin 1 homolog, cysteine knot superfamily

3.86

7.14

3.

Gja1

Gap junction protein, α1 (connexin 43)

3.49

7.10

4.

Zic3

Zic family member 3 heterotaxy 1

2.98

5.59

5.

Dnmt3b

DNA (cytosine-5)-methyltransferase 3β

2.26

6.25

6.

Sfrp1

Secreted frizzled-related protein 1

2.01

8.80

7.

Kiaa1573

KIAA1573 protein

1.98

2.48

8.

Dppa4

Developmental pluripotency associated 4

1.97

2.80

9.

Sox2

SRY (sex determining region Y)-box 2

1.86

12.44

10.

Foxo1a

Forkhead box O1A (rhabdomyosarcoma)

1.85

9.15

11.

Hmgb1

High-mobility group box 1

1.84

1.71

12.

Ctbp2

C-terminal binding protein 2

1.77

9.16

13.

Lin28

Lin-28 homolog (C. elegans)

1.52

20.32

14.

Utf1

Undifferentiated embryonic cell transcription factor

1.21

9.28

15.

Lefty1

Left-right determination factor 1

1.06

8.72

  1. Only entries with spot intensity in hESC sample >100 and Log2 ratio >1 are shown. Entries are sorted based on average Log2 ratio (after filtering for expression in all 4 technical replicates). S.E.M., standard error of the mean expressed as percentage of the mean.
  2. a Italics indicates genes down-regulated (< -1.0 Log2 ratio) in dopaminergic differentiation experiment. Nanog is down-regulated with Log2 ratio < -0.6.