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Table 1 Over-represented GO classes from the 'Molecular Function' and 'Biological Process' hierarchies observed among genes involved in fusion events

From: Denoising inferred functional association networks obtained by gene fusion analysis

GO Molecular Function Class

Number of domains found

Domains with GO Annotation

Percentage in fusion events

Percentage in all domains

Log Odds Expectation

receptor activity

122299

720242

0.170

0.017

3.349

protein transporter activity

180926

720242

0.251

0.029

3.120

small protein conjugating activity

5566

720242

0.008

0.001

2.798

microtubule motor activity

2780

720242

0.004

0.001

1.797

channel or pore class transporter activity

11394

720242

0.016

0.009

0.832

transcription factor activity

185303

720242

0.260

0.161

0.675

site-specific recombinase activity

3732

720242

0.005

0.003

0.636

extracellular matrix structural constituent

1242

720242

0.002

0.001

0.634

group translocator activity

1742

720242

0.002

0.002

0.122

other classes

205258

720242

0.285

  

GO Biological Process Class

     

cell communication

25613

416772

0.061

0.010

2.674

regulation of cellular process

48082

416772

0.115

0.055

1.068

regulation of development

4082

416772

0.010

0.007

0.510

cellular physiological process

34681

416772

0.083

0.059

0.493

regulation of physiological process

205318

416772

0.493

0.356

0.468

other classes

98996

416772

0.238

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