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Figure 3 | BMC Genomics

Figure 3

From: Mosquito transcriptome changes and filarial worm resistance in Armigeres subalbatus

Figure 3

12 K-means Cluster Analysis of features changing in response to B. malayi infection (y-axis, log-scale) over time (x-axis) colored by significance (red = more significant; green = less significant). K-means clustering was used to group genes with similar transcriptional patterns. Cluster six (numbered) contains 517 features, including 26 features with known immune activity, e.g., AMPs, pattern recognition molecules, serine proteases, etc. Clusters were constructed so that the average behavior in each group was distinct from any other group. This serves as a means to implicate unknowns in processes based on temporal transcriptional behavior, and based on semblance to other transcripts/pathways that maintain a similar profile.

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