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Table 1 List of 123 genes identified by SAGE in P. berghei salivary gland sporozoites

From: Serial Analysis of Gene Expression in Plasmodium berghei salivary gland sporozoites

   times found      
  Tag ID d14 d18 total GeneDB ID Known as Sporozoite expression Pf orthologue Predicted Pb/Pf protein domain and/or function
group 1 tag 335 60 39 99 PB402615.00.0*   d Pfgenefinder_63r  
  tag 183 6 89 95 PB100551.00.0 UIS4 a, d -- SP, TM
  tag 190 9 59 68 PB107461.00.0 UIS7 d -- TM
  tag 269 6 25 31 PB000374.03.0 TRAP d, 1, P PF13_0201 SP, vWA-like, TSP1
  tag 226 11 13 24 PB001063.00.0 S23 d, 1 PF08_0088 Pb-reticulocyte binding, SP, TM
group 2 tag 435 10 7 17 PB000252.01.0 S13, SPECT2 d, Pb, 1, P PFD0430c SP, MAC/Perforin domain
  tag 168 4 12 16 PB000317.00.0*   d, 1, P PF08_0008 SP, TM, GPI
  tag 146 8 8 16 PB000881.01.0 S21/PbTRSP d, 1, P PFA0200w TM, TSP1
  tag 112 11 2 13 PB000649.01.0 ECP1 Δ, 1, P PFB0325c Papain family cysteine protease
  tag 110 2 11 13 PB104017.00.0 S12 d -- SP
  tag 200 2 9 11 PB000400.01.0* SIS1 Δ, 1 PFE0395c Pf38, Sexual stage antigen, SP, TM, GPI
  tag 75 3 8 11 PB000484.00.0 UIS10/PbPL a PFF1420w Phosphatidylcholine-sterol acyltransferase
  tag 50 4 6 10 PB000891.00.0 Pbs36p d, 1 PFD0215c Pf52, Sexual stage antigen, SP
group 3 tag 76 1 8 9 PB104912.00.0*   d, 1 PF11_0283 SP, TM
  tag 264 3 5 8 AB125370 SPECT d, 1, P MAL13P1.212 SP
  tag 278 4 4 8 PB000757.02.0 SIS2 Δ, 1, P PF14_0425 Fructose-1, 6-bisphosphate aldolase
  tag 319 1 7 8 PB108190.00.0* UIS1 a -- Serine/Threonine protein kinases, 9 TM
  tag 136 2 5 7 PB100963.00.0   d -- Guanylyl cyclase, TM
  tag 245 0 6 6 PB000780.01.0*   d, 1 PFI1230c 4 TM, asparagine-rich
  tag 530 0 5 5 PB000264.00.0*   d PF14_0044 SP
  tag 118 0 5 5 PB000411.03.0* SIS3 Δ --  
  tag 294 1 4 5 PB000464.00.0 S25 d, 1, P PFL0545w Kinesin-related protein
  tag 280 0 5 5 PB000817.02.0   d, 1, P PF08_0054 Heat shock 70 kDa proteinn
  tag 268 1 4 5 PB001070.03.0   d PFF0685c Fe-only hydrogenase
  tag 193 1 4 5 PB101172.00.0   d --  
  tag 92 2 2 4 PB000161.03.0   d, 1 PFI0955w sugar transporter, 6TM
  tag 201 0 4 4 PB000787.03.0 SIS4 Δ, 1 PFI0320w Arginase family
  tag 101 0 4 4 PB105090.00.0 SIS5 Δ -- TM
  tag 233 1 3 4 PB106293.00.0*   d MAL13P1.365 SNARE
  tag188 2 2 4 PB107843.00.0* SIS6 Δ, 1 PF10_0290 TM
  tag 62 3 1 4 PB108391.00.0   d, 1, P PF08_0072 TM
  tag 276 1 3 4 PB000632.00.0 SIS7 Δ, 1 PF14_0518 nifU protein, putative
  tag 354 3 0 3 PB000175.03.0* SIS8 Δ, 1 PFD0915w TM
  tag 171 1 2 3 PB000416.02.0   d, 1 PFD0825c RNA-binding protein of pumilio/mpt5 family
  tag 326 2 1 3 PB000422.00.0   d, 1, P PF07_0126  
  tag 213 0 3 3 PB000468.02.0 SIS9 Δ, 1 PFL0335c Eukaryotic translation initiation factor 5
  tag 197 0 3 3 PB000626.00.0   d, 1 PF14_0224 PP1-like protein serine/threonine phosphatase
  tag 68 1 2 3 PB000674.01.0 SIS10 Δ, 1, P PF13_0058 RNA recognition motif
  tag 170 0 3 3 PB000876.00.0   Pb, 1, P MAL8P1.78 Small heat shock protein
  tag 236 0 3 3 PB000892.00.0 Pbs 36 Δ, 1 PFD0210c Pbs36, Sexual stage antigen, PS
  tag 20 0 3 3 PB000911.00.0* SIS11 Δ, 1 PFE0965c Vacuolar ATP synthetase, 4 TM
  tag 8 1 2 3 PB001101.02.0 SIS12 ΔΔ PF14_0395  
  tag 119 0 3 3 PB001143.02.0 SIS13 Δ, 1, P PF14_0083 Ribosomal protein S8e
  tag 122 1 2 3 PB001247.02.0 S14 d, 1, P PFL0370w  
  tag 127 0 3 3 PB001432.02.0 SIS14 Δ, 1 PFE0340c Peptidase S54, rhomboid, 7 TM
  tag 155 3 0 3 PB001575.02.0 SIS15 Δ, 1 PFB0270w SP, TM, Fe-S metabolism associated domain
  tag 150 0 3 3 PB104165.00.0   d, 1 PFI0675w  
  tag 305 0 3 3 PB104461.00.0   d -- SP, TM
  tag 350 0 3 3 PB105607.00.0   d -- 2 TM
  tag 106 1 2 3 PB105732.00.0   d -- TM
  tag 196 0 3 3 PB106033.00.0 SIS16 Δ, 1 PF10_0296  
  tag 41 1 2 3 PB107193.00.0* SIS17 ΔΔ PFF1195c  
  tag 121 1 2 3 PB108098.00.0   d -- TM
  tag 157 2 1 3 PB300784.00.0   d, 1 MAL8P1.154  
  tag 362 0 2 2 PY01277** SIS18 ΔΔ PFL2080c  
  tag 142 0 2 2 PB000006.00.0 SIS19 Δ, 1 PFE0995c  
  tag 265 0 2 2 PB000064.03.0 SIS20 ΔΔ PFB0510w 3 TM
  tag 143 0 2 2 PB000092.02.0 UIS2 a, 1, P PF14_0614  
  tag 355 1 1 2 PB000094.03.0 SIS21 Δ, 1, P MAL12P1.180 Arginyl-tRNA synthetase
  tag 15 1 1 2 PB000111.01.0   d, 1, P MAL12P1.63  
  tag 57 1 1 2 PB000120.01.0 SIS22 Δ, P PFC1065w  
  tag 26 1 1 2 PB000133.00.0 SIS23 Δ --  
  tag 59 0 2 2 PB000171.01.0 SIS24 Δ --  
  tag 339 0 2 2 PB000178.02.0 SIS25 Δ, 1 PFE0810c 40S ribosomal subunit protein S14
  tag 139 0 2 2 PB000207.01.0 SIS26 Δ, 1 PFL1050w SP, TRAF-like
  tag 221 0 2 2 PB000297.01.0 SIS27 Δ, 1 PF11_0251 SP, Endoplasmic reticulum oxidoreductin
  tag 12 0 2 2 PB000307.01.0 UIS9-7 a, 1 PFE0935c RNA-binding protein
  tag 134 0 2 2 PB000352.00.0 SIS28 Δ, 1 PF11_0150 SP, 6TM, Rhomboid family, SecY protein
  tag 51 2 0 2 PB000352.02.0   d, 1, P PFL2440w DNA repair protein rhp16
  tag 317 1 1 2 PB000354.03.0   d, 1 PF10_0283 TM
  tag 285 0 2 2 PB000396.01.0 SIS29 Δ, 1 PFC0330w PDZ domain protein
  tag 292 0 2 2 PB000412.02.0 SIS30 Δ, 1 PFI0750c  
  tag 17 0 2 2 PB000424.02.0   d, 1 PF11_0358 DNA-directed RNA polymerase, beta subunit
  tag 320 0 2 2 PB000450.03.0 SIS31 Δ, 1 MAL13P1.148 myosin
  tag 54 0 2 2 PB000530.00.0   d, 1 PFE0400w ankyrin
  tag 277 0 2 2 PB000553.03.0   d, 1 PF13_0161  
  tag 303 1 1 2 PB000591.00.0 SIS32 ΔΔ PFC0125w DNAJ domain protein
  tag 184 0 2 2 PB000599.03.0 SIS33 Δ, 1 PF14_0681 Diacylglycerol kinase
  tag 34 0 2 2 PB000604.01.0   d PFF0840w  
  tag 87 0 2 2 PB000610.02.0 SIS34 Δ, 1 PFL2390c  
  tag 204 0 2 2 PB000624.01.0 SIS35 Δ, 1 PF13_0261 ATP binding protein
  tag 128 0 2 2 PB000650.00.0 SIS36 Δ, 1, P PF14_0446 Fasciclin domain
  tag 58 0 2 2 PB000675.02.0 SIS37 ΔΔ PFF1450w Sec14-like cytosolic factor
  tag 144 1 1 2 PB000709.00.0 SIS38 Δ, 1 PF14_0181 Calmodulin
  tag 289 2 0 2 PB000798.02.0 MAEBL d, 1, P PF11_0486 MAEBL, SP, TM
  tag 88 0 2 2 PB000807.01.0 SIS39 Δ, 1 PFD0485w Ferlin like protein
  tag 353 0 2 2 PB000811.01.0   d, 1 MAL7P1.125  
  tag 80 1 1 2 PB000837.02.0 SIS40 Δ, 1 PF14_0695 DNA-directed RNA polymerase, alpha subunit
  tag 116 0 2 2 PB000857.01.0 SIS41 Δ, 1, P PF11_0183 GTP-binding nuclear protein ran/tc4
  tag 238 0 2 2 PB000874.02.0 SIS42 Δ, 1 MAL8P1.142 Proteasome beta-subunit
  tag 79 0 2 2 PB000903.01.0 SIS43 Δ, 1 PF11_0197 SP, Ankyrin repeat
  tag 227 0 2 2 PB000904.01.0 SIS44 Δ, 1 PF11_0196 SP
  tag 206 0 2 2 PB000927.03.0 SIS45 Δ, 1 MAL12P1.113 Heat shock protein DNAJ homologue Pfj4
  tag 210 0 2 2 PB000941.01.0 SIS46 Δ, 1 PF10_0096 Octapeptide repeat
  tag 349 0 2 2 PB000994.02.0*   d, 1 PFL1690w  
  tag 218 0 2 2 PB001066.02.0   d, 1 PF10_0140 SPRY
  tag 228 0 2 2 PB001080.02.0 SIS47 Δ, 1 PFL0870w SP, TM, TSP, thrombospondin-related 3
  tag 267 1 1 2 PB001118.02.0 UIS4-6 d, 1 PFA0170c TM
  tag 27 0 2 2 PB001120.00.0 SIS48 Δ, 1 MAL13P1.150 2 TM
  tag 6 0 2 2 PB001130.00.0 SIS49 Δ, 1, P MAL8P1.133 Glycosyltransferase family 28 protein
  tag 124 1 1 2 PB001157.02.0 SIS50 Δ, 1 MAL8P1.67 PIN domain like
  tag 301 0 2 2 PB001178.02.0 SIS51 Δ, 1 PFD0300w  
  tag 123 0 2 2 PB001253.00.0 SIS52 Δ, 1 PFD0360w Zinc finger
  tag 331 0 2 2 PB001305.00.0 SIS53 Δ, 1, P PF11_0168 Serine esterase
  tag 70 1 1 2 PB001374.02.0   d, 1, P MAL13P1.304 Malaria antigen, metalloendopeptidase
  tag 31 0 2 2 PB001507.02.0 SIS54 ΔΔ PFB0620w  
  tag 312 0 2 2 PB001517.02.0   d PFF0800w SP, TM, vWFA, TSP1
  tag 43 1 1 2 PB100341.00.0 SIS55 Δ --  
  tag 93 1 1 2 PB101083.00.0   d --  
  tag 61 2 0 2 PB101148.00.0 SIS56 Δ --  
  tag 114 2 0 2 PB101408.00.0 SIS57 Δ, 1 PFE1260c TM
  tag 56 2 0 2 PB101596.00.0 SIS58 Δ --  
  tag 342 0 2 2 PB102211.00.0 SIS59 Δ --  
  tag 318 1 1 2 PB102277.00.0   d --  
  tag 71 0 2 2 PB103980.00.0 SIS60 Δ -- 2 TM
  tag 271 0 2 2 PB105487.00.0   d -- 2 TM
  tag 35 0 2 2 PB106484.00.0 SIS61 Δ, 1 PF14_0449  
  tag 208 0 2 2 PB108086.00.0 SIS62 Δ --  
  tag 151 0 2 2 PB000618.02.0 SIS63 Δ PFD0725c arsenical pump-driving ATPase, putative
  tag 179 1 1 2 PB300567.00.0 SIS64 ΔΔ PFL2420w  
  tag 85 0 2 2 PB300953.00.0 SIS65 ΔΔ MAL8P1.121  
  tag 33 1 1 2 PB301273.00.0   d, 1 PFL1695c  
  tag 47 0 2 2 PB000460.01.0 SIS66 Δ, 1 PFC0750w SP
  1. (a) : mRNA detected in P. berghei sporozoites [14].
  2. (d): mRNA detected in P. yoelii sporozoites [13].
  3. Pb : detected by proteomics in P. berghei sporozoites [11].
  4. P : detected by proteomics in P. falciparum sporozoites [10].
  5. 1 : detected in P. falciparum sporozoites with microarrays [9].
  6. SP : signal peptide.
  7. TM : transmembrane domain.
  8. ** : orthologue of a P. yoelli gene for which a P. berghei gene is not yet annotated.
  9. SIS: new S porozoite expressed gene I dentified by S AGE, this work.
  10. Δ : no rodent Plasmodium sporozoite ESTs or proteomics data.
  11. ΔΔ : no sporozoite ESTs or detection by microarrays or proteomics in Plasmodium species.