TY - JOUR AU - Ulvé, Vincent M. AU - Sevin, Emeric W. AU - Chéron, Angélique AU - Barloy-Hubler, Frédérique PY - 2007 DA - 2007/12/19 TI - Identification of chromosomal alpha-proteobacterial small RNAs by comparative genome analysis and detection in Sinorhizobium meliloti strain 1021 JO - BMC Genomics SP - 467 VL - 8 IS - 1 AB - Small untranslated RNAs (sRNAs) seem to be far more abundant than previously believed. The number of sRNAs confirmed in E. coli through various approaches is above 70, with several hundred more sRNA candidate genes under biological validation. Although the total number of sRNAs in any one species is still unclear, their importance in cellular processes has been established. However, unlike protein genes, no simple feature enables the prediction of the location of the corresponding sequences in genomes. Several approaches, of variable usefulness, to identify genomic sequences encoding sRNA have been described in recent years. SN - 1471-2164 UR - https://doi.org/10.1186/1471-2164-8-467 DO - 10.1186/1471-2164-8-467 ID - Ulvé2007 ER -