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Table 4 Disease-related proteins with counterparts in U. maydis

From: The fungus Ustilago maydis and humans share disease-related proteins that are not found in Saccharomyces cerevisiae

Protein Function MIPS ID Diseases U. maydis* S. cerevisiae* Ref.**
ACADM acyl-CoA dehydrogenase Um01049 acyl-CoA dehydrogenase deficiency 58.0 11.6 [68]
ACADS acyl-CoA dehydrogenase Um04833 acyl-CoA dehydrogenase deficiency 35.2 11.2 [69]
BZRP/PBR Benzodiazepine receptor Um06406 Cancer 27.4 10.1 [70]
CES1 Carboxylesterase Um06071 Cancer 27.6 9.3 [71]
CLPTM1 unknown Um02586 Cleft lip development 30.5 11.1 [72]
DDC Dopa decarboxylase Um06083 Parkinsons 34.7 11.0 [73]
DOCK3 Dedicator of cytokinesis 3 Um01178 Attention deficit hyperactivity disorder 23.1 12.3 [74]
EPHX1 Epoxide hydrolase Um01938 Cancer 36.6 10.1 [74]
GCDH glutaryl-CoA dehydrogenase Um01335 glutaryl-CoA dehydrogenase deficiency 54.1 13.9 [75]
HEXA Hexosaminidase A Um00695 Tay-Sachs disease 20.1 12.7 [76]
HMGCL Methylglutaryl CoA lyase Um02001 methylglutaric CoA lyase deficiency 43.6 11.4 [77]
PIMT/PCMT1 Methyl-transferase Um11483 Type 1 diabetes 48.9 9.3 [78]
PRSS16 serine protease Um10091 Diabetes mellitus/susceptibility to autoimmunity 20.7 6.6 [79]
UGCG Glucosyl-ceramide synthase Um04496 induced apoptosis 22.3 8.1 [80]
  1. Identification tag for search at the MIPS server [13]
  2. * Values are given as percent identity to human protein, all the U. maydis hits are best bidirectional
  3. ** Reference for the human protein/disease