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Figure 3 | BMC Genomics

Figure 3

From: Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex genetic alterations in cervical cancer

Figure 3

FISH of metaphase preparations depicting copy number alterations. A) CaSki – 5 chromosomes 5 (centromere 5-blue; TRIO-green; SKP2-red); one isochromosome 5p (yellow arrow), 2 translocations of RP11-1150G22, encompassing TRIO (green arrow) and 2 translocations of RP11-624K2, encompassing SKP2 (red arrow). B) CaSki – 3 chromosomes 8 (centromere 8-red, TUSC3-green) with loss of one copy the BACs encompassing TUSC3, RP11-44L18/184C1 (green arrow). C) HeLa – 4 chromosomes 20 (centromere 20-blue, ZNF-217-red, CYP24A1-green); one isochromosome 20q (yellow arrow).

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