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Table 5 Aberrations determined by FISH analysis at chromosomes 5, 8 and 20.

From: Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex genetic alterations in cervical cancer

Gene

Location

BAC clone

1

7

8

10a

10b

11-

11+

S

C

H

SKP2

5p13.2

RP11-624K2

-

-

-

-

-

-

-

G

G

G

TRIO

5p15.2

RP11-1150G22

-

-

-

-

-

-

-

G

G

G

hTERT

5p15.33

RP11-117B23

-

-

-

-

-

-

-

G

G

G

GDNF

5p13.2

RP11-914H3

-

-

-

-

-

-

-

G

G

G

ANKH

5p15.2

RP11-99I1

-

G

-

G

G

G

-

G

G

G

TUSC3

8p22

44L18/184C1

-

-

-

L

-

L

L

L

L

-

ZNF-217

20q13.2

RP4-724E16

G

-

G

G

G

-

-

-

-

G

CYP24A1

20q13.2

RP5-1075G21

G

-

G

G

G

-

-

-

-

G

MYBL2

20q13.12

RP11-153L9

G

-

G

G

G

-

-

-

-

G

AIB1

20q12

RP11-1151C1

G

-

G

G

G

-

-

-

-

G

  1. (-) no aberration; G – gain; L – loss. Cell lines: 1 – CSCC1; 7 – CSCC7; 8 – CC8; 10a – CC10A; 10b – CC10b; 11 – CC11-; 11+ – CC11+; S – SiHa, C – CaSki, H – HeLa.
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BMC Genomics

ISSN: 1471-2164

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