Figure 1
From: Sequence features responsible for intron retention in human
Sequence logos for 5' and 3' splice sites of retained introns, constitutive and skipped exons. The logos show splice sites flanking: (A) Low-RIF retained introns (1515 splice site pairs), (B) High-RIF retained-introns (250 pairs), (C) Only high-RIF retained introns flanked by GT..AG (240 pairs), (D) Constitutive exons (those that did not present any evidence of involvement in any type of alternative splicing, 90185 pairs), (E) Skipped exons with RIF < 1 (31414 pairs), (F) Skipped exons with RIF > 1 (9567 pairs). The RIF for exon skipping was calculated analogously for intron retention (RIF = number of cDNAs skipping the exon/cDNAs with the exon).