Figure 5

GGG/class 2 FAS-ESS densities in retained and non-retained introns and variation with splice site strength. Panels (A) and (B): Distribution of the frequency of retained and non-retained introns with varying densities of GGG (A) and class 2 FAS-ESSs (B). The low-RIF group presents a bias for introns with high GGG density, whereas the high-RIF group presents the opposite trend. Panels (C) and (D): Mean GGG (C) and class 2 FAS-ESSs (D) densities in non-retained and retained introns flanked by splice sites with different S&S scores. Only classes of S&S scores with more than 5 sequences were plotted.