Skip to main content

Table 3 Asbestos-related genes. Previously identified potential asbestos-associated genes represented in significant clusters of all cell lines. (Affymetrix IDs are available upon request)

From: Gene expression profiles in asbestos-exposed epithelial and mesothelial lung cell lines

Asbestos-associated gene A549 cluster Beas-2B cluster MeT5A cluster Chr. loc
Mesothelioma-associated genes*
BIRC5 5 13 2 17q25
BTG2 5 7 3 1q32
CALU 9 8 3 7q32
CALU 9 8 3 7q32
COL1A1 5 10 2 17q21.33
COL4A1 5 8 2 13q34
COL5A1 5 14 2 9q34
COL6A2 5 3 2 21q22
FN1 9 6 3 2q34
HMGB1 9 3 2 13q12
HNRPH1 5 7 2 5q35
IGFBP4 4 10 3 17q21.2
KIBRA 5 6 3 5q34
LU 2 3 2 19q13
LU 2 10 3 19q13
NF2 5 7 2 22q12
PDLIM7 2 7 2 5q35
PDLIM7 5 7 2 5q35
PEG10 9 8 3 7q21
POM121 4 13 2 7q11
PTPRF 5 13 2 1p34
PXN 5 13 2 12q24
TPD52L1 5 6 1 6q22.31
TP53 5 7 2 17p13
TXN 11 1 1 9q31
VEGF 9 8 3 6p12
VEGF 9 8 3 6p12
VIL2 8 16 2 6q25.3
Human homologs of asbestos associated murine genes
BIRC4 6 7 1 Xq25
BIRC4 7 13 1 Xq25
BMP2 5 14 1 20p12
CD44 9 14 2 11p13
CSNK2A1 9 13 2 20p13
CTSB 1 14 1 8p22
FAS 1 8 1 10q24
FAS 1 8 1 10q24
IQGAP1 9 6 3 15q26
MAP4K4 1 8 3 2q11.2
PLEC1 9 6 2 8q24
PTPN14 9 6 3 1q32
PTPRF 5 13 2 1p34
RHOA 9 6 2 3p21
TP53 5 7 2 17p13
TRAM1 5 8 2 8q13
VAV2 5 13 2 9q34
Other asbestos-associated genes
ADD3 5 8 3 10q24
CASP8 9 6 2 2q33.1
CDK10 5 13 2 16q24
COL12A1 9 8 2 6q13-14.1
FOSL2 2 3 3 2p23
IKBKB 9 16 2 8p11
KRAS 7 13 1 12p12
L1CAM 2 11 2 Xq28
MAPK1 3 5 3 22q11
MAPK1 9 6 2 22q11
MAPK1 9 6 2 22q11
NFKB2 5 13 3 10q24
PCDHGA6 § 12 10 3 5q31
PRKCD 5 6 3 3p21
  1. * [17, 36–39]
  2. [6, 20]
  3. [4, 18, 19, 55, 56]
  4. § The probe also corresponds to PCDHGC3 /// PCDHGB4 /// PCDHGA8 /// PCDHGA12 /// PCDHGC5 /// PCDHGC4 /// PCDHGB7 /// PCDHGB6 /// PCDHGB5 /// PCDHGB3 /// PCDHGB2 /// PCDHGB1 /// PCDHGA11 /// PCDHGA10 /// PCDHGA9 /// PCDHGA7 /// PCDHGA6 /// PCDHGA5 /// PCDHGA4 /// PCDHGA3 /// PCDHGA2 /// PCDHGA1