Directional preference of LDSS-positive hexamers. When the corresponding complementary sequence was not found in the LDSS-positive group, the hexamer was counted as "uniq", which means orientation-sensitive. When found, the sequence was counted as "comp", meaning direction-insensitive. The number of both hexamers were counted according to the peak position from the TSS, and summarized in a bar graph. The inset graph is an enlargement to show more detail around the TSS.