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Table 1 Differentially expressed genes of MSC after high grade expansion.

From: Gene expression profiling of human mesenchymal stem cells derived from bone marrow during expansion and osteoblast differentiation

Passage 2 vs passage 5 Acc.No Gene name log2 ratio Fold-change
XM_016240 hypothetical protein xp_016240; loc87477//Homo sapiens similar to keratinocyte growth factor-like protein, group II – human (LOC158116) 0.92 1.89
NM_006211_1 proenkephalin; penk 1.58 2.99
NM_001854_1 collagen, type xi, alpha 1; col11a1 1.27 2.41
BC010956_1 similar to fibroblast growth factor 7 (keratinocyte growth factor) 1.03 2.04
NM_000612_1 Insulin-like growth factor 2 (somatomedin A); igf2 1.59 3.01
NM_031476_1 hypothetical protein dkfzp434b044; dkfzp434b044 1.34 2.53
U52914_1 b219ob receptor isoform hub219.3 precursor 1.13 2.19
NM_006379_1 sema domain, immunoglobulin domain (ig), short basic domain, secreted, (semaphorin) 3c; sema3c -0.69 0.62
NM_002546_1 osteoprotegerin; tnfrsf11b -1.03 0.49
Passage 5 vs passage 10 Acc.No    
NM_019105_1 tenascin xb 0.85 1.80
  1. List of differentially expressed genes after statistical analysis by modified version of the regularized t-test [64] (p < 0.05) for ten donors (passage 2 vs. passage 5) and five donors (passage 5 vs. passage 10).
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BMC Genomics

ISSN: 1471-2164

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