From: Gene function in early mouse embryonic stem cell differentiation
key | Probe set id | Gene | Gene description | Function/process/component (GO)1 |
---|---|---|---|---|
D6 | 1418133_at | Bcl3 | B-cell leukemia/lymphoma 3 | DNA binding; transcription factor activity; regulation of transcription, DNA-dependent; nucleus; |
D6 | 1418025_at | Bhlhb2 | basic helix-loop-helix domain containing, class B2 | DNA binding; protein binding; nucleus; regulation of transcription, DNA-dependent; transcriptional repressor activity; negative regulation of transcription, DNA-dependent; |
D6 | 1419076_a_at | Brca2 | breast cancer 2 | nucleic acid binding; protein binding; nucleus; cytoplasm; DNA repair; response to DNA damage stimulus; double-strand break repair via homologous recombination; synaptonemal complex; single-stranded DNA binding; DNA replication; chromatin remodeling; apoptosis; regulation of S phase of mitotic cell cycle; mitotic checkpoint; transcriptional activator activity; regulation of transcription; |
D6 | 1416039_x_at | Cyr61 | cysteine rich protein 61 | regulation of cell growth; patterning of blood vessels; protein binding; insulin-like growth factor binding; extracellular; extracellular space; chemotaxis; cell adhesion; heparin binding; growth factor binding; sensory perception; |
D6 | 1417394_at | Klf4 | Kruppel-like factor 4 (gut) | nucleic acid binding; DNA binding; nucleus; regulation of transcription, DNA-dependent; zinc ion binding; transcription factor activity; transcriptional activator activity; transcriptional repressor activity; negative regulation of transcription, DNA-dependent; |
D6 | 1417395_at | Â | Â | Â |
D6 | 1435458_at | Pim1 | proviral integration site 1 | protein kinase activity; protein serine/threonine kinase activity; protein-tyrosine kinase activity; ATP binding; nucleus; protein amino acid phosphorylation; cell growth and/or maintenance; kinase activity; transferase activity; |
D6 | 1437100_x_at | Pim3 | proviral integration site 3 | protein kinase activity; protein serine/threonine kinase activity; ATP binding; protein amino acid phosphorylation; kinase activity; transferase activity; |
D6 | 1451069_at | Â | Â | Â |
D6 | 1423078_a_at | Sc4mol | sterol-C4-methyl oxidase-like | C-4 methyl sterol oxidase activity; catalytic activity; endoplasmic reticulum; plasma membrane; fatty acid metabolism; metabolism; steroid metabolism; integral to membrane; sterol biosynthesis; oxidoreductase activity; |
D6 | 1415823_at | Scd2 | stearoyl-Coenzyme A desaturase 2 | fatty acid biosynthesis; superoxide metabolism; lipid biosynthesis; stearoyl-CoA 9-desaturase activity; copper, zinc superoxide dismutase activity; iron ion binding; oxidoreductase activity; metal ion binding; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; endoplasmic reticulum; membrane; integral to membrane; endoplasmic reticulum |
D6 | 1416576_at | Socs3 | suppressor of cytokine signaling 3 | regulation of cell growth; signal transduction; intracellular signaling cascade; regulation of protein amino acid phosphorylation; protein binding; negative regulation of insulin receptor signaling pathway; |
D6 | 1455899_x_at | Â | Â | Â |
D6 | 1456212_x_at | Â | Â | Â |
D6 | 1450989_at | Tdgf1 | teratocarcinoma-derived growth factor | activation of MAPK; extracellular; extracellular space; epidermal growth factor receptor signaling pathway; growth factor activity; positive regulation of cell proliferation; determination of anterior/posterior axis, embryo; extrinsic to plasma membrane; |
D12 | 1460330_at | Anxa3 | annexin A3 | phospholipase inhibitor activity; calcium ion binding; calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity; |
D12 | 1449141_at | Fblim1 | filamin binding LIM protein 1 | protein binding; cytoskeleton; cell adhesion; zinc ion binding; regulation of cell shape; |
D12 | 1427238_at | Fbxo15 | F-box protein 15 | protein binding; ubiquitin cycle; SCF ubiquitin ligase complex; |
D12 | 1426858_at | Inhbb | inhibin beta-B | hormone activity; extracellular; growth factor activity; cell growth and/or maintenance; growth; ovarian follicle development; defense/immunity protein activity; cytokine activity; response to external stimulus; protein homodimerization activity; host cell surface receptor binding; positive regulation of follicle-stimulating hormone secretion; negative regulation of follicle-stimulating hormone secretion; negative regulation of hepatocyte growth factor biosynthesis; |
D12 | 1451021_a_at | Klf5 | Kruppel-like factor 5 | nucleic acid binding; DNA binding; nucleus; regulation of transcription, DNA-dependent; zinc ion binding; angiogenesis; transcription factor activity; protein binding; microvillus biogenesis; positive regulation of transcription; |
D12 | 1418153_at | Lama1 | laminin, alpha 1 | morphogenesis of an epithelial sheet; receptor binding; structural molecule activity; extracellular matrix structural constituent; protein binding; extracellular matrix; basement membrane; basal lamina; laminin-1; cell adhesion; cell surface receptor linked signal transduction; histogenesis; regulation of cell adhesion; regulation of cell migration; regulation of embryonic development; establishment of epithelial cell polarity; |
D12 | 1424719_a_at | Mapt | microtubule-associated protein tau | protein binding; cytoskeletal regulatory protein binding; cytoskeleton; microtubule associated complex; microtubule-based process; microtubule stabilization; microtubule; actin filament organization; microtubule-based movement; |
D12 | 1449590_a_at | Mras | muscle and microspikes RAS | GTP binding; small GTPase mediated signal transduction; small monomeric GTPase activity; RAS small monomeric GTPase activity; |
D12 | 1417760_at | Nr0b1 | nuclear receptor subfamily 0, group B, member 1 | DNA binding; transcription factor activity; steroid hormone receptor activity; receptor activity; ligand-dependent nuclear receptor activity; nucleus; cytoplasm; regulation of transcription, DNA-dependent; negative regulation of transcription; transcriptional repressor activity; |
D12 | 1448612_at | Sfn | stratifin | regulation of progression through cell cycle; regulation of cyclin dependent protein kinase activity; protein domain specific binding; cytoplasm; |
D12 | 1423505_at | Tagln | transgelin | muscle development; NOT cytoskeleton organization and biogenesis; |
D12 | 1418756_at | Trh | thyrotropin releasing hormone | hormone activity; neuropeptide hormone activity; protein binding; extracellular; extracellular space; thyrotropin-releasing hormone activity; hormone mediated signaling; |
D12 | 1450641_at | Vim | vimentin | structural molecule activity; intermediate filament; type III intermediate filament; intermediate filament-based process; oxygen transporter activity; oxygen transport; |
U12 | 1427202_at | 4833442J19Rik | RIKEN cDNA 4833442J19 gene | S-adenosylmethionine-dependent methyltransferase activity;nucleus; |
U12 | 1416077_at | Adm | adrenomedullin | hormone activity; neuropeptide hormone activity; extracellular; extracellular space; neuropeptide signaling pathway; |
U12 | 1449324_at | Ero1l/LOC434220 | ERO1-like (S. cerevisiae) | endoplasmic reticulum; electron transport; protein folding; transport; membrane; oxidoreductase activity; integral to endoplasmic reticulum membrane; |
U12 | 1421317_x_at | Myb | myeloblastosis oncogene | regulation of cell cycle; G1/S transition of mitotic cell cycle; DNA binding; transcription factor activity; nucleus; regulation of transcription, DNA-dependent; calcium ion transport; cell growth and/or maintenance; viral assembly; |
U12 | 1425926_a_at | Otx2 | orthodenticle homolog 2 (Drosophila) | DNA binding; transcription factor activity; protein binding; nucleus; regulation of transcription, DNA-dependent; regulation of transcription from Pol II promoter; development; central nervous system development; organogenesis; anterior/posterior pattern formation; dorsal/ventral pattern formation; transcription regulator activity; forebrain development; midbrain development; eye photoreceptor cell fate commitment; cell fate commitment; |
U12 | 1418391_at | Phf21a | PHD finger protein 21A | transcription; regulation of transcription, DNA-dependent; DNA binding; protein binding; zinc ion binding |
U12 | 1417288_at | Plekha2 | pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2 | phosphatidylinositol binding; nucleus; lipid binding; membrane; |
U6 | 1448129_at | Arpc5 | actin related protein 2/3 complex, subunit 5 | structural constituent of cytoskeleton; cytoplasm; Arp2/3 protein complex; cell motility; actin filament organization; actin cytoskeleton; DNA binding; electron transport; heme binding; lamellipodium; regulation of actin filament polymerization; regulation of transcription; |
U6 | 1434642_at | Dhrs8 | dehydrogenase/reductase (SDR family) member 8 | extracellular space; metabolism; oxidoreductase activity; |
U6 | 1452670_at | Myl9 | myosin, light polypeptide 9, regulatory | calcium ion binding; muscle myosin; regulation of muscle contraction; muscle development; structural constituent of muscle; myosin; motor activity; |
U6 | 1426596_a_at | Smn1 | survival motor neuron 1 | nucleic acid binding; RNA binding; nucleus; cytoplasm; mRNA processing; spliceosome assembly; |
U6 | 1423054_at | Wdr1 | WD repeat domain 1 | actin binding; cytoskeleton; perception of sound; actin cytoskeleton; |
U6 | 1437591_a_at | Â | Â | Â |
U6 | 1450851_at | Â | Â | Â |