Figure 5

Functional characterisation of regionally enriched gene sets and CNS-signature genes: Molecular Function. Heat-map demonstrating the significance of over- and under-represented Panther molecular functions. Red colour signifies an over-representation of genes mapping to a certain term, blue colour an under-representation and white a representation as expected, based on the overall distribution on the array. The colour intensity indicates the negative log of the significance p-value. Numbers presented on the heat map display the percentage of genes within a gene set that map to a certain term. The first column states the overall distribution of a term among the 25,971 genes with detectable expression in the data set, followed by each regional gene set and finally the 'CNS-signature' gene set. FCx, fronto-medial cortex; TCx, temporal cortex; OCx, occipital cortex; HiF, Hippocampus; Str, Striatum; Cb, cerebellum; CNS, 'CNS-signature' genes.