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Table 7 Comparison of the patulin – and citrinin-induced genes contributing to DNA repair

From: Evaluation of toxicity of the mycotoxin citrinin using yeast ORF DNA microarray and Oligo DNA microarray

 

Fold Induction

  

Systematic Name

Patulin

Citrinin

Common Name

MIPS_Description

YDL059C

5.7

1.8

RAD59

Recombination and DNA repair protein

YGL163C

5.3

1.0

RAD54

DNA-dependent ATPase of the Snf2p family

YGR209C

4.4

3.0

TRX2

Thioredoxin II

YDR092W

4.0

1.2

UBC13

E2 ubiquitin-conjugating enzyme

YER142C

3.9

1.5

MAG1

3-methyladenine DNA glycosylase

YHL024W

3.7

1.1

RIM4

No sporulation

YFL014W

3.7

0.9

HSP12

Heat shock protein

YPR193C

3.7

1.2

HPA2

Histone and other Protein Acetyltransferase

YKL145W

3.5

1.3

RPT1

26S proteasome regulatory subunit

YMR173W

3.4

2.9

DDR48

Heat shock protein

YAR007C

3.4

1.0

RFA1

DNA replication factor A, 69 KD subunit

YPL194W

3.1

1.1

DDC1

DNA damage checkpoint protein

YLR043C

3.0

1.4

TRX1

Thioredoxin I

YOR023C

2.9

1.0

AHC1

Component of the ADA histone acetyltransferase comple

YEL037C

2.8

1.1

RAD23

Nucleotide excision repair protein (ubiquitin-like protein)

YMR302C

2.8

0.9

PRP12

Involved in early maturation of pre-rRNA

YNL312W

2.7

1.2

RFA2

DNA replication factor A, 36 kDa subunit

YIL143C

2.7

1.1

SSL2

DNA helicase

YJR052W

2.6

1.1

RAD7

Nucleotide excision repair protein

YOL068C

2.4

0.7

HST1

Silencing protein

YGR231C

2.4

1.0

PHB2

Prohibitin

YPR023C

2.3

1.2

EAF3

Esa1p-associated factor

YML032C

2.3

1.1

RAD52

Recombination and DNA repair protein

YIR025W

2.2

1.2

MND2

Subunit of anaphase-promoting complex

YGL201C

2.1

1.0

MCM6

Involved in replication

YMR201C

2.1

0.9

RAD14

Nucleotide excision repair protein

YNL250W

2.0

1.2

RAD50

DNA repair protein

YCR086W

2.0

1.5

CSM1

Involved in nuclear migration