Table 5 TGF-β regulated genes (38) in A549 involved in MAP kinase signalling
Acc No | DAVID Gene Name | 1 hr | 4 hr | 12 hr |
|---|---|---|---|---|
H09832 | ACTIVIN A RECEPTOR, TYPE IB | 1.01 ± 0.17 | 1.66 ± 0.29 | 1.17 ± 0.06 |
N27681 | HEAT SHOCK 70 KDA PROTEIN 1A | 1.12 ± 0.01 | 1.46 ± 0.18 | 1.42 ± 0.08 |
H73255 | MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 6 | 0.84 ± 0.31 | 1.04 ± 0.07 | 1.49 ± 0.11 |
N42722 | GUANINE NUCLEOTIDE BINDING PROTEIN (G PROTEIN), GAMMA 12 | 1.44 ± 0.04 | 1.5 ± 0.09 | 1.28 ± 0.17 |
AA039598 | RIBOSOMAL PROTEIN S6 KINASE, 90 KDA, POLYPEPTIDE 1 | 1.16 ± 0.13 | 1.21 ± 0.02 | 1.32 ± 0.02 |
AA030029 | PROTEIN KINASE C, ALPHA | 1.33 ± 0.23 | 1.56 ± 0.08 | 1.36 ± 0.03 |
H73472 | CELL DIVISION CYCLE 42 (GTP BINDING PROTEIN, 25 KDA) | 1.24 ± 0.27 | 1.33 ± 0.07 | 1.56 ± 0.01 |
H62639 | HEAT SHOCK 70 KDA PROTEIN 8 | 1.29 ± 0.01 | 1.68 ± 0.18 | 1.37 ± 0 |
H23019 | TRANSFORMING GROWTH FACTOR, BETA RECEPTOR I (ACTIVIN A RECEPTOR TYPE II-LIKE KINASE, 53 KDA) | 1.09 ± 0.01 | 2.53 ± 0.07 | 2.11 ± 0.41 |
AA088648 | FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME) | 1.45 ± 0.24 | 1.97 ± 0.08 | 1.77 ± 0.09 |
AV747676 | V-AKT MURINE THYMOMA VIRAL ONCOGENE HOMOLOG 3 (PROTEIN KINASE B, GAMMA) | 1.06 ± 0.13 | 1.46 ± 0.05 | 1.18 ± 0.01 |
AI500475 | RAS GUANYL RELEASING PROTEIN 1 (CALCIUM AND DAG-REGULATED) | 1.31 ± 0.05 | 1.37 ± 0 | 1.41 ± 0.07 |
R86053 | NUCLEAR FACTOR OF KAPPA LIGHT POLYPEPTIDE GENE ENHANCER IN B-CELLS 2 (P49/P100) | 0.99 ± 0.12 | 0.9 ± 0.07 | 1.44 ± 0.09 |
BE502112 | RIBOSOMAL PROTEIN S6 KINASE, 90 KDA, POLYPEPTIDE 3 | 0.37 ± 0.1 | 0.29 ± 0.05 | 0.41 ± 0.06 |
H23109 | FIBROBLAST GROWTH FACTOR 1 (ACIDIC) | 0.94 ± | 1.36 ± 0.01 | 1.13 ± 0.05 |
AA127934 | PROTEIN KINASE, X-LINKED | 1.21 ± 0.07 | 1.38 ± 0.01 | 1.35 ± 0.07 |
H89206 | PROTEIN KINASE, CAMP-DEPENDENT, CATALYTIC, BETA | 1.18 ± 0.08 | 1.42 ± 0.04 | 1.25 ± 0.03 |
R14348 | MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 | 1.45 ± 0.09 | 1.22 ± 0.17 | 1.03 ± 0.06 |
BM924824 | RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 (RHO FAMILY, SMALL GTP BINDING PROTEIN RAC1) | 1.39 ± 0 | 1.41 ± 0.06 | 1.28 ± 0.18 |
H11708 | MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 | 1.38 ± 0.02 | 1.54 ± 0.1 | 1.24 ± 0.17 |
R36401 | FILAMIN B, BETA (ACTIN BINDING PROTEIN 278) | 0.96 ± 0.02 | 1.17 ± 0.11 | 1.33 ± 0.01 |
BI758537 | MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE C (MYOCYTE ENHANCER FACTOR 2C) | 1.77 ± 0.42 | 1.25 ± | 1.36 ± 0.09 |
W56249 | ACTIVATING TRANSCRIPTION FACTOR 2 | 1.25 ± 0.13 | 1.5 ± 0.02 | 1.72 ± 0.18 |
AA034981 | INTERLEUKIN 1 RECEPTOR, TYPE I | 0.37 ± 0.08 | 0.4 ± 0.02 | 0.29 ± 0.04 |
AA056664 | V-AKT MURINE THYMOMA VIRAL ONCOGENE HOMOLOG 1 | 1.34 ± 0.15 | 1.44 ± 0.05 | 1.36 ± 0.07 |
H20677 | MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 INTERACTING PROTEIN 1 | 1.13 ± 0.15 | 0.96 ± 0.1 | 1.6 ± 0.01 |
BM999610 | V-JUN SARCOMA VIRUS 17 ONCOGENE HOMOLOG (AVIAN) | 1.57 ± 0.26 | 2.13 ± 0.01 | 1.66 ± 0.18 |
BE781203 | CALCIUM CHANNEL, VOLTAGE-DEPENDENT, ALPHA 1G SUBUNIT | 1.13 ± 0.03 | 1.02 ± 0 | 1.44 ± 0 |
T83272 | RAS P21 PROTEIN ACTIVATOR 2 | 0.96 ± 0.08 | 1.12 ± 0.18 | 1.33 ± 0.02 |
T75436 | MITOGEN-ACTIVATED PROTEIN KINASE 10 | 1.16 ± 0.17 | 1.22 ± 0.05 | 1.37 ± 0.07 |
W70006 | CELL DIVISION CYCLE 25B | 1.47 ± 0.1 | 1.15 ± 0.05 | 1.38 ± 0.08 |
R32409 | PHOSPHOLIPASE A2, GROUP V | 1.14 ± 0.27 | 1.27 ± 0.01 | 1.5 ± 0.07 |
AW961873 | CALCIUM CHANNEL, VOLTAGE-DEPENDENT, GAMMA SUBUNIT 4 | 1.45 ± 0.15 | 1.23 ± 0.17 | 1.02 ± 0 |
BI752921 | PLATELET-DERIVED GROWTH FACTOR RECEPTOR, BETA POLYPEPTIDE | 1.43 ± 0.09 | 1.03 ± 0.02 | 1.09 ± 0.07 |
BQ055308 | RIBOSOMAL PROTEIN L4 | 1.44 ± 0.05 | 1.26 ± 0.04 | 1.43 ± 0.08 |
R14058 | PROTEIN KINASE C, BETA 1 | 1.54 ± 0.06 | 1.08 ± 0.01 | 1.15 ± 0 |
BQ016117 | V-FOS FBJ MURINE OSTEOSARCOMA VIRAL ONCOGENE HOMOLOG | 1.48 ± 0.26 | 1.44 ± 0.04 | 1.29 ± 0.06 |
W05234 | CALCIUM CHANNEL, VOLTAGE-DEPENDENT, BETA 3 SUBUNIT | 1.4 ± 0.07 | 1.15 ± 0.05 | 1.27 ± 0 |