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Table 8 TGF-β regulated genes (36) in A549 involved in focal adhesion

From: Expression profiling of genes regulated by TGF-beta: Differential regulation in normal and tumour cells

Acc No

DAVID Gene Name

1 hr

4 hr

12 hr

N45505

VAV 1 ONCOGENE

0.64 ± 0.37

0.41 ± 0.11

0.31 ± 0.01

AA046597

INTEGRIN, BETA 4

1.26 ± 0.21

1.1 ± 0.19

1.8 ± 0.18

R52046

ACTININ, ALPHA 4

1.26 ± 0.68

1.21 ±

1.81 ± 0.21

AA030029

PROTEIN KINASE C, ALPHA

1.33 ± 0.23

1.56 ± 0.08

1.36 ± 0.03

BE738680

RAS HOMOLOG GENE FAMILY, MEMBER A

1.24 ± 0.11

1.4 ± 0.06

1.51 ± 0.03

H73472

CELL DIVISION CYCLE 42 (GTP BINDING PROTE IN, 25 KDA)

1.24 ± 0.27

1.33 ± 0.07

1.56 ± 0.01

W17002

INTEGRIN, ALPHA V (VITRONECTIN RECEPTOR, ALPHA POLYPEPTIDE, ANTIGEN CD51)

1.21 ± 0.06

2.32 ± 0.29

2.73 ± 0.28

AV747676

V-AKTMURINE THYMOMA VIRAL ONCOGENE HOMOLOG 3 (PROTEIN KINASE B, GAMMA)

1.06 ± 0.13

1.46 ± 0.05

1.18 ± 0.01

BM912016

P21(CDKN1A)-ACTIVATED KINASE 4

1.29 ± 0.03

1.1 ± 0.23

1.54 ± 0.03

BM008467

ZYXIN

0.95 ± 0.1

1.16 ± 0.14

1.41 ± 0.07

AA037738

HEPATOCYTE GROWTH FACTOR (HEPAPOIETIN A; SCATTER FACTOR)

1.43 ± 0.07

1.36 ± 0.03

1.06 ± 0.13

H89256

LAMININ, BETA 1

1.44 ± 0.02

1.4 ± 0.02

1.12 ± 0.07

AA026831

KINASE INSERT DOMAIN RECEPTOR (A TYPE III RECEPTOR TYROSINE KINASE)

1.17 ± 0.1

1.34 ± 0.02

1.06 ± 0.01

BM924824

RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 (RHO FAMILY, SMALL GTP BINDING PROTEIN RAC1)

1.39 ± 0

1.41 ± 0.06

1.28 ± 0.18

AA122291

COLLAGEN, TYPE V, ALPHA 2

1.1 ± 0.08

1.19 ± 0.13

1.43 ± 0.11

R36401

FILAMIN B, BETA (ACTIN BINDING PROTEIN 278)

0.96 ± 0.02

1.17 ± 0.11

1.33 ± 0.01

R20452

CALPAIN 10

1.19 ± 0.21

1.08 ± 0.06

1.5 ± 0.01

H15287

P21(CDKN1A)-ACTIVATED KINASE 6

1.47 ± 0.08

1.21 ± 0.05

1.57 ± 0.04

W24540

FERM, RHOGEF AND PLECKSTRIN DOMAIN PROTEIN 2

1.28 ± 0.06

1.37 ± 0.1

1.46 ± 0.05

T39460

PROTEIN PHOSPHATASE 1, CATALYTIC SUBUNIT, ALPHA ISOFORM

1.35 ± 0.17

1.38 ± 0.04

1.49 ± 0.15

AA056664

V-AKT MURINE THYMOMA VTRAL ONCOGENE HOMOLOG 1

1.34 ± 0.15

1.44 ± 0.05

1.36 ± 0.07

AA127854

INTEGRIN, ALPHA 5 (FIBRONECTIN RECEPTOR, ALPHA POLYPEPTIDE)

1.4 ± 0.08

1.12 ± 0.03

1.22 ± 0.06

BG497332

THROMBOSPONDIN 1

0.87 ± 0.01

1.1 ± 0.1

2.24 ± 0.11

R25275

GLYCOGEN SYNTHASE KINASE 3 BETA.

1.15 ± 0.16

1.36 ± 0.04

1.23 ± 0.06

BQ016959

COLLAGEN, TYPE IV, ALPHA 2

1.18 ± 0.07

1.3 ± 0

1.33 ± 0.09

BM999610

V-JUN SARCOMA VIRUS 17 ONCOGENE HOMOLOG (AVIAN)

1.57 ± 0.26

2.13 ± 0.01

1.66 ± 0.18

AA044582

INTEGRIN, BETA 8

0.33 ± 0.03

0.26 ± 0.04

0.25 ± 0

T75436

MITOGEN-ACTIVATED PROTEIN KINASE 10

1.16 ± 0.17

1.22 ± 0.05

1.37 ± 0.07

AA069424

INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR

1.5 ± 0.09

1.16 ± 0.07

1.02 ± 0.05

BI752921

PLATELET-DERIVED GROWTH FACTOR RECEPTOR, BETA POLYPEPTIDE

1.43 ± 0.09

1.03 ± 0.02

1.09 ± 0.07

N99223

INTEGRIN, ALPHA 9

1.46 ± 0.12

1.08 ±

1.29 ± 0.01

BQ017489

ACTININ, ALPHA 1

1.57 ± 0.22

1.24 ± 0.1

1.5 ± 0.1

AA010526

GLUCOCORTICOID RECEPTOR DNA BINDING FACTOR 1

1.44 ± 0.14

1.03 ± 0.04

1.31 ± 0

R14058

PROTEIN KINASE C, BETA 1

1.54 ± 0.06

1.08 ± 0.01

1.15 ± 0

AA005247

MET PROTO-ONCOGENE (HEPATOCYTE GROWTH FACTOR RECEPTOR)

1.68 ± 0.34

1.3 ± 0.03

1.14 ± 0.07

AA043909

PTK2 PROTEIN TYROSINE KINASE 2

0.52 ± 0.11

0.52 ± 0.12

0.34 ± 0

  1. For description see legend of table 5
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BMC Genomics

ISSN: 1471-2164

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