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Table 1 Pairwise sequence comparison of the coding and the 5'-flanking sequence of mammalian HL genes.

From: Comparative genomics and experimental promoter analysis reveal functional liver-specific elements in mammalian hepatic lipase genes

  upstream regulatory sequence  
cDNA sequence 81   53 53 61 57 56 hedgehoga
  79 76   86 64 55 59 mouse
  79 76 92   63 57 57 rat
  85 82 79 79   94 94 rhesusa
  85 82 80 80 96   98 chimp
  85 82 79 79 96 99   human
  rabbitb hedgehog mouse rat rhesus chimp human  
  1. Sequence identity (%) was determined by pairwise alignment using the DNAMAN software package (optimal alignment; gap open penalty 10.0, gap extension penalty 5.0). cDNA sequence was from the translation start ATG up till the stopcodon; the upstream regulatory region was from -1400 up till the translation start ATG.
  2. a: Because of a gap in upstream regulatory region of the public sequence of the rhesus monkey and hedgehog HL gene (Ensembl e ! 42: Dec 2006), alignments with the rhesus and hedgehog sequence were done with the sequence from -900 and -1000 up till the start ATG, respectively.
  3. b:the rabbit HL cDNA sequence was taken from [38].