Figure 5

Abundance functional profile. Shown is the fraction of proteins which are involved in different functional categories in different abundance ranges. The first data point shows the functional breakdown of the 50 most abundant proteins, the second data point corresponds to the 100 most abundant proteins, and so on. Note that the fractions relative to the number of proteins (e.g. 50, 100...) do not sum up to 1 since a protein can have assigned multiple functions like protein synthesis and with binding function. The functional categories shown in the legend are the FunCat top level classifications as outlined in the Methods sections. In this plot all 1103 proteins – inclusive the 53 ribosomal proteins – are shown. Since the plot is based on relative ranking it is robust with respect to the observed copy number variability of these most abundant proteins.