Table 5 Comparison of features associated with protein aggregation between high abundant proteins and the remaining detected proteins. The high abundant group is defined as described in Material and Methods.
From: Protein abundance profiling of the Escherichia coli cytosol
Property | Low abundant proteins Mean (Median) | High abundant proteins Mean (Median) | P-value KS-, MW-test |
|---|---|---|---|
Protein length (in amino acids) | 386 (327) | 309 (252) | 10-6, 10-7 |
Number of alternating hydrophobic-/hydrophilic stretches (> = 5aa) | 11.7 (9.0) | 9.5 (8.0) | 0.03, 10-4 |
pI distance from neutrality | 1.52 (1.50) | 1.69 (1,84) | 0.003, 0.01 |
Hydrophobicity (Kyte-Doolite scale) | -0.20 (-0.21) | -0.25 (-0.24) | 0.17, 0.08 |