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Table 2 Domain analysis of transcription factors.

From: Two different classes of co-occurring motif pairs found by a novel visualization method in human promoter regions

Domain name

Occurrence of domain

# of TF

Odds ratio

P-value

 

Class 1

serine-rich

55

3

3.00

3.52E-13

dimerization

86

6

2.46

1.86E-15

basic

82

5

2.24

1.73E-12

helix

81

5

2.12

5.87E-11

HLH

51

3

2.04

1.11E-06

zinc_finger

151

8

1.89

6.16E-18

leucine_zipper

65

4

1.70

1.97E-05

glutamine-rich

85

6

1.65

1.90E-06

trans_activation

91

6

1.61

2.12E-06

 

Class 2

glutamine-/proline-rich

335

3

2.85

4.65E-65

serine-rich

344

3

2.66

5.85E-60

alanine-rich

321

3

2.48

2.22E-49

proline-rich

551

5

1.73

8.47E-39

POU-domain

294

3

1.67

1.98E-17

serine-/threonine-rich

524

5

1.65

3.26E-31

leucine_zipper

443

4

1.64

3.56E-25

forkhead

311

3

1.55

1.65E-14

 

All

serine-rich

723

4

3.46

3.29E-187

glutamine-/proline-rich

540

3

2.85

1.20E-103

proline-rich

1,419

8

2.77

7.95E-302

glycine-rich

885

5

2.59

2.51E-153

alanine-rich

533

3

2.55

2.14E-85

dimerization

893

5

2.24

3.48E-118

helix

876

5

2.01

1.98E-90

HLH

535

3

1.88

3.08E-44

basic

711

4

1.70

4.24E-45

leucine_zipper

743

4

1.70

2.65E-47

serine-/threonine-rich

869

5

1.70

4.98E-56

  1. Shown are the domain names, the frequency of the domains in the hub-TFs (i.e., the TFs in Table 1) for class 1, 2, and all of co-occurring motif pairs. The domains are ordered by odds ratio.