Figure 7From: Comprehensive transcriptional profiling of prion infection in mouse models reveals networks of responsive genesSummary of the genes, pathways and biological processes that characterize the key events in prion pathogenesis. Schematic of the postulated molecular and cellular pathogenic mechanisms triggered during prion-induced neurodegeneration. Genes in red are those significantly up-regulated during disease, while green type indicates down-regulated genes.Back to article page