Table 1 Bi-codon frequencies. The third column lists those codons c for the first amino acid (AA1) in a consecutive pair which lead to a stop in frame -1. The overall relative frequency of c as a codon for AA1 is given in the fifth column. The relative frequency of c in the specific context AA1-AA2 is given in column six. The penultimate column shows the enrichment of the codon c in this context; an enrichment > 1 indicates that this codon is more frequently used for AA1 when it leads to a stop in frame -1 than in the average case. Probability (P) values were assigned using the χ² test, and significance determined with a Bonferroni multiple testing correction (15 analyses). Single (*) and triple (***) asterisks indicate significance at the 0.05 and 0.001 levels, respectively.

From: Bioinformatics prediction of overlapping frameshifted translation products in mammalian transcripts