Table 4 Top functions associated with significant networks identified by IPA and number of focus genes at each time point.
Top functions | Time | |||
|---|---|---|---|---|
T1 | T2 | T4 | T8 | |
Gene Expression | 9 | 12 | 178 | 297 |
Molecular Transport | 9 | - | 81 | 372 |
Drug Metabolism | 9 | - | 31 | 83 |
Cancer | - | 47 | 386 | 357 |
Connective Tissue Development and Function | - | 27 | 103 | 152 |
Cell Cycle | - | 24 | 246 | 432 |
Cellular Development | - | 23 | 144 | 64 |
Cell Death | - | 23 | 141 | 205 |
Cell Morphology | - | 23 | 91 | 58 |
Cellular Movement | - | 15 | 92 | 125 |
Cellular Assembly and Organization | - | 15 | 82 | 358 |
Post-Translational Modification | - | 13 | 75 | 79 |
Small Molecule Biochemistry | - | 13 | 64 | 324 |
Amino Acid Metabolism | - | 13 | 56 | 219 |
Neurological Disease | - | 12 | 59 | 147 |
Organismal Injury and Abnormalities | - | 12 | 30 | 56 |
Cellular Growth and Proliferation | - | 11 | 93 | 114 |
Connective Tissue Disorders | - | 11 | 15 | 21 |
Cell Signaling | - | - | 223 | 662 |
DNA Replication Recombination and Repair | - | - | 183 | 194 |
Genetic Disorder | - | - | 128 | 218 |
Nervous System Development and Function | - | - | 98 | 166 |
Hematological Disease | - | - | 92 | 89 |
Protein Synthesis | - | - | 88 | 204 |
Dermatological Diseases and Conditions | - | - | 82 | 175 |
Hematological System Development and Function | - | - | 81 | 116 |
Lipid Metabolism | - | - | 79 | 363 |
Cell-To-Cell Signaling and Interaction | - | - | 76 | 122 |
Skeletal and Muscular Disorders | - | - | 76 | 33 |
Immune Response | - | - | 71 | 246 |
Cardiovascular Disease | - | - | 70 | 80 |
Cellular Function and Maintenance | - | - | 61 | 263 |
Embryonic Development | - | - | 54 | 180 |
Endocrine System Development and Function | - | - | 53 | 62 |
Immunological Disease | - | - | 44 | 54 |
RNA Post-Transcriptional Modification | - | - | 43 | 122 |
Nucleic Acid Metabolism | - | - | 39 | 130 |
Reproductive System Development and Function | - | - | 35 | 26 |
Tissue Development | - | - | 34 | 73 |
Protein Trafficking | - | - | 34 | 63 |
Protein Folding | - | - | 32 | 31 |
Carbohydrate Metabolism | - | - | 31 | 136 |
Cardiovascular System Development and Function | - | - | 31 | 127 |
Organismal Development | - | - | 29 | 30 |
Cellular Compromise | - | - | 28 | 96 |
Organ Morphology | - | - | 28 | 91 |
Vitamin and Mineral Metabolism | - | - | 27 | 61 |
Skeletal and Muscular System Development and Function | - | - | 25 | 33 |
Developmental Disorder | - | - | 18 | 33 |
Inflammatory Disease | - | - | 16 | 95 |
Nutritional Disease | - | - | 16 | 30 |
Infectious Disease | - | - | 14 | 65 |
Metabolic Disease | - | - | 12 | 89 |
Viral Function | - | - | 61 | - |
Reproductive System Disease | - | - | 48 | - |
Ophthalmic Disease | - | - | 32 | - |
Hair and Skin Development and Function | - | - | 31 | - |
Organ Development | - | - | 31 | - |
Cardiac Fibrosis | - | - | 30 | - |
Viral Infection | - | - | 30 | - |
Cardiac Enlargement | - | - | 28 | - |
DNA Replication | - | - | 20 | - |
Cardiac Pulmonary Embolism | - | - | 17 | - |
Dermatological Diseases and Condition | - | - | 17 | - |
Cardiac Necrosis/Cell Death | - | - | 16 | - |
Digestive System Development and Function | - | - | 16 | - |
Hepatic System Disease | - | - | 14 | - |
Tumor Morphology | - | - | 13 | - |
Protein Degradation | - | - | - | 119 |
Energy Production | - | - | - | 84 |
Gastrointestinal Disease | - | - | - | 65 |
Behavior | - | - | - | 61 |
Immune and Lymphatic System Development and Function | - | - | - | 61 |
Renal Necrosis/Cell Death | - | - | - | 33 |
Renal and Urological System Development and Function | - | - | - | 32 |
Endocrine System Disorders | - | - | - | 31 |
Cardiac Hypertrophy | - | - | - | 30 |
Organismal Survival | - | - | - | 28 |
Free Radical Scavenging | - | - | - | 27 |
Respiratory System Development and Function | - | - | - | 25 |
Tissue Morphology | - | - | - | 23 |
Hepatic System Development and Function | - | - | - | 21 |
Focus genes | 12 | 98 | 1474 | 2887 |