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Table 4 Top functions associated with significant networks identified by IPA and number of focus genes at each time point.

From: Transcriptomic analysis of the dialogue between Pseudorabies virus and porcine epithelial cells during infection

Top functions Time
  T1 T2 T4 T8
Gene Expression 9 12 178 297
Molecular Transport 9 - 81 372
Drug Metabolism 9 - 31 83
Cancer - 47 386 357
Connective Tissue Development and Function - 27 103 152
Cell Cycle - 24 246 432
Cellular Development - 23 144 64
Cell Death - 23 141 205
Cell Morphology - 23 91 58
Cellular Movement - 15 92 125
Cellular Assembly and Organization - 15 82 358
Post-Translational Modification - 13 75 79
Small Molecule Biochemistry - 13 64 324
Amino Acid Metabolism - 13 56 219
Neurological Disease - 12 59 147
Organismal Injury and Abnormalities - 12 30 56
Cellular Growth and Proliferation - 11 93 114
Connective Tissue Disorders - 11 15 21
Cell Signaling - - 223 662
DNA Replication Recombination and Repair - - 183 194
Genetic Disorder - - 128 218
Nervous System Development and Function - - 98 166
Hematological Disease - - 92 89
Protein Synthesis - - 88 204
Dermatological Diseases and Conditions - - 82 175
Hematological System Development and Function - - 81 116
Lipid Metabolism - - 79 363
Cell-To-Cell Signaling and Interaction - - 76 122
Skeletal and Muscular Disorders - - 76 33
Immune Response - - 71 246
Cardiovascular Disease - - 70 80
Cellular Function and Maintenance - - 61 263
Embryonic Development - - 54 180
Endocrine System Development and Function - - 53 62
Immunological Disease - - 44 54
RNA Post-Transcriptional Modification - - 43 122
Nucleic Acid Metabolism - - 39 130
Reproductive System Development and Function - - 35 26
Tissue Development - - 34 73
Protein Trafficking - - 34 63
Protein Folding - - 32 31
Carbohydrate Metabolism - - 31 136
Cardiovascular System Development and Function - - 31 127
Organismal Development - - 29 30
Cellular Compromise - - 28 96
Organ Morphology - - 28 91
Vitamin and Mineral Metabolism - - 27 61
Skeletal and Muscular System Development and Function - - 25 33
Developmental Disorder - - 18 33
Inflammatory Disease - - 16 95
Nutritional Disease - - 16 30
Infectious Disease - - 14 65
Metabolic Disease - - 12 89
Viral Function - - 61 -
Reproductive System Disease - - 48 -
Ophthalmic Disease - - 32 -
Hair and Skin Development and Function - - 31 -
Organ Development - - 31 -
Cardiac Fibrosis - - 30 -
Viral Infection - - 30 -
Cardiac Enlargement - - 28 -
DNA Replication - - 20 -
Cardiac Pulmonary Embolism - - 17 -
Dermatological Diseases and Condition - - 17 -
Cardiac Necrosis/Cell Death - - 16 -
Digestive System Development and Function - - 16 -
Hepatic System Disease - - 14 -
Tumor Morphology - - 13 -
Protein Degradation - - - 119
Energy Production - - - 84
Gastrointestinal Disease - - - 65
Behavior - - - 61
Immune and Lymphatic System Development and Function - - - 61
Renal Necrosis/Cell Death - - - 33
Renal and Urological System Development and Function - - - 32
Endocrine System Disorders - - - 31
Cardiac Hypertrophy - - - 30
Organismal Survival - - - 28
Free Radical Scavenging - - - 27
Respiratory System Development and Function - - - 25
Tissue Morphology - - - 23
Hepatic System Development and Function - - - 21
Focus genes 12 98 1474 2887
  1. *The same focus gene may exist in different top functions.
  2. § The number of focus genes from the Qiagen_NRSP8 microarray is reported at each time point for each top function.