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Figure 1 | BMC Genomics

Figure 1

From: Analyzing stochastic transcription to elucidate the nucleoid's organization

Figure 1

a, b and c – The autocorrelation functions for data set A, when all three replicons are actively transcribed and translated. Figure 1a shows the autocorrelation function for the megaplasmid pSymA (blue curve) when the plasmid is actively transcribed (and translated; data set A). The red curve shows the autocorrelation function when the genes' positions were randomly assigned. The Y-axis has been cropped at an autocorrelation of 0.15 for a clearer visual interpretation; the blue curve starts at an autocorrelation of 0.27 for a gene distance of one. Maxima (positive correlation) and minima (negative or anti-correlation) can be clearly distinguished, with a strong anti-correlation for genes that lie opposite of each other on the chromosome (a gene distance of around 650). Similarly, Figures 1b and 1c show the results for the chromosome and the megaplasmid pSymB, respectively, when both are actively transcribed (and translated; data set A). As can be seen, the autocorrelation functions for the three replicons are similar. Note: The figures are all at the same scale to better illustrate the different sizes of the three replicons. All Y-axes have been cropped at a value of 0.15 for (visual) clarity's sake.

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