Figure 2

Multiple sequence alignment of Hog domains, part 1. Multiple sequence alignment in this and other figures was carried out using first MUSCLE and then imported into Clustal_X. Manual adjustments to the alignment were carried out using SeaView. Color coding was modified from default Clustal_X color coding by marking all cysteine residues in yellow, small hydrophobic residues in light blue and large hydrophobic residues in cyan blue. The Hint domain, as well as the C-terminal SRR or ARR regions are indicated above the alignment. Motifs A, B, F, J, K, and L are indicated with red rectangles underneath the alignment. Species abbreviations are shown in Table 3. Note that not all sequences in this alignment are complete.