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Figure 20 | BMC Genomics

Figure 20

From: Evolution of hedgehog and hedgehog-related genes, their origin from Hog proteins in ancestral eukaryotes and discovery of a novel Hint motif

Figure 20

Summary of the evolution of hh and hh -related genes. For detailed discussion of the evolution of the Hog proteins see text. The right side shows the different types of ORFs found in different organisms. The sizes are not to scale. The "Hedge" domain is marked in green, the Qua domain in orange, and the Hog domain in black, with yellow bars representing the conserved cysteine residues. T stands for poly-threonine repeats. Red 'X's mark branches where a gene loss occurred.

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