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Figure 8 | BMC Genomics

Figure 8

From: Evolution of hedgehog and hedgehog-related genes, their origin from Hog proteins in ancestral eukaryotes and discovery of a novel Hint motif

Figure 8

Phylogenetic tree of Ground and Ground-like domains. A multiple sequence alignment of Ground and Ground-like domains (see Additional file 8) was used to generate a Neighbor joining tree with the default settings of Clustal_X. For grd-1, grd-2 and grd-11 the four Ground domains were extracted manually prior to alignment; the R1 to R4 postscripts indicate the repeat number. B. malayi sequences are highlighted in light blue. This tree is unrooted. Results of 1000 bootstrap trials are shown.

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