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Table 5 Shortest path length in the regulatory network.

From: Topological comparison of methods for predicting transcriptional cooperativity in yeast

 

CTFPs

Co-functional TF pairs

Co-regulatory TF pairs

Co-functional ∩ co-regulatory TF pairs

Random TF pairs

Method

Mean

Mean

p-value

Mean

p-value

Mean

p-value

Mean

p-value

Method N

3.731

3.970

5.196·10 -1

3.292

4.162·10 -1

5.000

4.779·10 -1

4.380

1.304·10 -1

Method B

3.500

3.970

3.498·10 -1

3.292

4.123·10 -1

5.000

5.483·10 -1

4.380

6.550·10 -2

Method T

2.846

3.970

5.882·10 -2

3.292

4.878·10 -1

5.000

1.641·10 -1

4.380

1.246·10 -2

Method C

3.258

3.970

7.551·10 -2

3.292

9.632·10 -1

5.000

2.659·10 -1

4.380

5.292·10-3

  1. Shortest path length between cooperative TF pairs in the regulatory network. The distribution of shortest path lengths between the CTFPs predicted by each method was compared to distributions in the other sets of TF pairs by means of a Mann-Whitney test. Font styles are as in Table 3.