Table 1 List of top 20 up and down regulated genes in the head kidney of trout, 24 and 72 hours after i.p. injection of LPS. Genes were selected for significant differential expression at p < 0.01 (FDR < 0.05). Values are expressed as FC, fold change.
24 hours UP | Â | Â | Â | 72 hours UP | Â | Â | Â |
|---|---|---|---|---|---|---|---|
Clone ID | Clone Name | FC | p | Clone ID | Clone Name | FC | p |
est03d11 | Unknown-42 | 8.42 | 0.000 | est03d11 | Unknown-42 | 3.81 | 0.000 |
est04b01 | Similar to rRNA (Vangl2) | 4.54 | 0.004 | est03e02 | Hypothetical-fish 15 | 3.39 | 0.001 |
EXOB1_H05 | Transposase-6 | 3.16 | 0.000 | est04e04 | MHC class 1b antigen | 3.17 | 0.006 |
EXOB2_D06 | NADH dehydrogenase subunit 5-1 | 2.76 | 0.000 | EXOB2_H06 | High affinity immunoglobulin epsilon receptor alpha | 2.73 | 0.003 |
est02g07 | Ig mu heavy chain disease protein | 2.73 | 0.001 | CA387837 | Nucleolar protein NAP57 | 2.27 | 0.000 |
est02a11 | Ig kappa chain V-IV region B17-2 | 2.71 | 0.002 | EXOB4_C11 | High affinity immunoglobulin gamma Fc receptor I precursor | 2.15 | 0.008 |
EST1-3A_G09 | Unknown-75 | 2.32 | 0.001 | ENH2_F09 | Beta-2-microglobulin-1 | 1.99 | 0.004 |
CA383564 | Coatomer epsilon subunit 1 | 2.25 | 0.001 | EXOB2_A09 | 60S ribosomal protein L5-2 | 1.80 | 0.005 |
est04e04 | MHC class 1b antigen | 2.24 | 0.007 | HST0001_C05 | Cell division control protein 42 homolog | 1.72 | 0.009 |
EST1-3A_F12 | Transposase-59 | 2.12 | 0.001 | EXOB3_F09 | MHC class I heavy chain-1 | 1.71 | 0.001 |
HK0002_D09 | Prothymosin alpha | 2.03 | 0.003 | est01g04 | 5-aminolevulinate synthase | 1.58 | 0.010 |
est02e09 | Ig heavy chain V-III region HIL | 2.00 | 0.005 | Â | Â | Â | Â |
EXOB4_D12 | Hpa repeat-1 | 1.99 | 0.001 | Â | Â | Â | Â |
HK0003_E06 | DnaJ homolog subfamily C member 9 | 1.96 | 0.005 | Â | Â | Â | Â |
HK0003_E08 | Unknown-194 | 1.90 | 0.007 | Â | Â | Â | Â |
est04g12 | Envelope protein | 1.90 | 0.004 | Â | Â | Â | Â |
HK0002_H08 | TATA-binding protein associated factor 2N | 1.79 | 0.003 | Â | Â | Â | Â |
CA387665 | Cytochrome P450 2J2 | 1.79 | 0.000 | Â | Â | Â | Â |
est01h01 | Unknown-19 | 1.76 | 0.009 | Â | Â | Â | Â |
est03b11 | Acidic leucine-rich nuclear phosphoprotein 32 A-1 | 1.68 | 0.008 | Â | Â | Â | Â |
24 hours DOWN | Â | Â | Â | 72 hours DOWN | Â | Â | Â |
EXOB2_D07 | Ependymin related protein-1 | -2.28 | 0.002 | est04c10 | Unknown-56 | -2.04 | 0.000 |
HST0001_C04 | Hemoglobin alpha chain | -2.42 | 0.004 | CA367764 | Calmodulin-1 | -2.13 | 0.001 |
EST1-3A_D08 | Glyceraldehyde-3-phosphate dehydrogenase-6 | -2.49 | 0.009 | est03c04 | Matrix metalloproteinase-9 | -2.21 | 0.000 |
EXOB1_H06 | CC chemokine SCYA110-2 | -2.55 | 0.005 | HKT0001_E07 | Actin, alpha skeletal 1 | -2.28 | 0.002 |
EST1-3A_H06 | Transcription factor jun-B-1 | -2.89 | 0.003 | est01f03 | Deltex protein 1 | -2.37 | 0.001 |
est03f08 | Transaldolase | -2.91 | 0.002 | est01e02 | Thymosin beta-4-1 | -2.73 | 0.002 |
EXOB2_H01 | Unknown-100 | -2.91 | 0.002 | EXOB3_G05 | Actin, cytoplasmic 2 | -2.78 | 0.000 |
est02f08 | Serine protease-like protein-1 | -2.97 | 0.000 | EST1-3A_D08 | Glyceraldehyde-3-phosphate dehydrogenase-6 | -3.14 | 0.000 |
EST1-3A_A09 | Serine protease-like protein-2 | -3.96 | 0.003 | EST1-3A_B03 | Hypothetical-fish 44 | -3.16 | 0.007 |
CA371363 | Glucose-6-phosphate isomerase-1 | -4.35 | 0.000 | CA348284 | CCAAT/enhancer binding protein beta | -3.22 | 0.003 |
HST0001_D08 | Beta-globin | -4.46 | 0.000 | CA374193 | Chemokine receptor CXCR4 | -3.71 | 0.000 |
est04e05 | Glutathione peroxidase-gastrointestinal | -4.54 | 0.000 | utu04f08 | Actin, alpha skeletal 5 | -3.81 | 0.001 |
est01c04 | Unknown-11 | -6.17 | 0.001 | KVkm2_F01 | Unknown-224 | -4.21 | 0.000 |
EXOB2_D05 | Matrix metalloproteinase 9-2 | -6.63 | 0.000 | est01f01 | DNA-binding protein inhibitor ID-1 | -4.64 | 0.000 |
est01e10 | Tolloid-like protein (nephrosin)-1 | -6.69 | 0.001 | est02f08 | Serine protease-like protein-1 | -4.64 | 0.001 |
CA348284 | CCAAT/enhancer binding protein beta | -7.36 | 0.006 | EST1-3A_A09 | Serine protease-like protein-2 | -5.52 | 0.000 |
est03c04 | Matrix metalloproteinase-9 | -7.44 | 0.000 | EXOB3_H01 | Matrix metalloproteinase-13 | -5.88 | 0.007 |
EXOB2_G12 | Tolloid-like protein (nephrosin)-2 | -9.26 | 0.000 | EXOB2_H01 | Unknown-100 | -12.08 | 0.000 |
EST1-3A_B03 | Hypothetical-fish 44 | -14.01 | 0.000 | est01e10 | Tolloid-like protein (nephrosin)-1 | -12.97 | 0.000 |
EXOB3_H01 | Matrix metalloproteinase-13 | -17.18 | 0.000 | EXOB2_G12 | Tolloid-like protein (nephrosin)-2 | -13.47 | 0.000 |