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Table 4 Over-represented gene ontology terms for sex-biased categories (log2 fold-change < 1,-> 1) within gonad-expressed genes. Significantly (p < 0.01) over-represented terms are shown in term-for-term comparisons. Subsequent adjustments with the Bonferroni correction for multiple comparisons are shown.

From: The unique genomic properties of sex-biased genes: Insights from avian microarray data

Location

Sex-bias

GO

Name

Process

p (padj)

Autosomal

Female

005576

Extracellular region

C

0.000 (0.075)

  

0005874

Microtubule

C

0.000 (0.21)

  

0005509

Calcium ion binding

M

0.002 (0.24)

  

0030705

Cytoskeletal-dependent intracellular transport

B

0.002 (0.99)

  

0007018

Microtubule-based movement

B

0.002 (1.00)

  

0007017

Microtubule-based process

B

0.003 (1.00)

  

0015630

Microtubule cytoskeleton

C

0.003 (1.00)

  

0044430

Cytockeletal part

C

0.004 (1.00)

  

0030136

Clathrin-coated vesicle

C

0.005 (1.00)

  

0048878

Chemical homeostasis

B

0.006 (1.00)

  

0006828

Iron ion transport

B

0.006 (1.00)

  

0050801

Ion homeostasis

B

0.006 (1.00)

  

0030286

Dynein complex

C

0.006 (1.00)

  

0030234

Enzyme regulator activity

M

0.01 (1.00)

 

Male

0016020

Membrane

C

0.000(0.034)

  

0005244

Voltage-gated ion channel activity

M

0.003 (1.000)

  

0005249

Voltage-gated potassium channel activity

M

0.003 (1.000)

  

0051536

Iron-sulfur cluster binding

M

0.003 (1.000)

  

0051540

Metal cluster binding

M

0.003 (1.000)

  

0004713

Protein-tyrosine kinase activity

M

0.004 (1.000)

  

0009055

Electron carrier activity

M

0.007 (1.000)

  

0016021

Integral to membrane

C

0.008 (1.000)

  

0031224

Intrinsic to membrane

C

0.008 (1.000)

  

0015020

Glucuronosyltransferase activity

M

0.008 (1.000)

  

0015018

Galactosylgalactosylxylosylprotein 3-beta glucuronosyltransferase activity

M

0.008 (1.000)

  

0007155

Cell adhesion

B

0.009 (1.000)

  

0022610

Biological adhesion

B

0.009 (1.000)

  

0044425

Membrane part

C

0.01 (1.000)

 

Unbiased

0044237

Cellular metabolic process

B

0.000 (0.11)

  

0044238

Primary metabolic process

B

0.000 (0.19)

  

0016881

Acid-amino acid ligase activity

M

0.000 (0.42)

  

005622

Ubiquitin cycle

C

0.000 (0.69)

  

0006512

Intracellular

B

0.000 (0.70)

  

0019787

Small conjugating protein ligase activity

M

0.001 (0.89)

  

0008152

Metabolic process

M

0.001 (1.00)

  

0016879

Ligase activity, forming carbon-nitrogen bonds

B

0.001 (1.00)

  

0043170

Macromolecule metabolic process

B

0.001 (1.00)

  

0016874

Ligase activity

M

0.001 (1.00)

  

0005736

Mitochondrion

C

0.002 (0.15)

  

0009056

Catabolic process

 

0.004 (0.24)

  

0019538

Protein metabolic process

 

0.004 (1.00)

  

0044248

Cellular catabolic process

 

0.005 (1.00)

  

0003676

Nucleic acid binding

 

0.005 (1.00)

  

0044429

Mitochondrial part

 

0.006 (1.00)

  

0043283

Biopolymer metabolic process

 

0.006 (1.00)

  

0006412

Translation

 

0.006 (1.00)

  

0044267

Cellular protein metabolic process

 

0.007 (1.00)

  

0043231

Intracellular membrane-bound organelle

 

0.008 (1.00)

  

0043227

Membrane-bound organelle

 

0.008 (1.00)

  

0044260

Cellular macromolecule metabolic process

 

0.008 (1.00)

  

0006396

RNA processing

 

0.009 (1.00)