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Table 1 GO categories with high promoter conservation. Terms of biological process are labeled as P, cellular component as C, molecular function as F.

From: Weak correlation between sequence conservation in promoter regions and in protein-coding regions of human-mouse orthologous gene pairs

GO term Number of genes P-value
P:development 649 0
P:regulation of transcription 602 1.67E-15
F:transcription factor activity 263 3.44E-15
P:transcription 640 4.11E-14
P:nervous system development 154 1.99E-10
P:organ development 213 2.30E-10
P:signal transduction 994 5.19E-10
F:DNA binding 628 3.19E-08
P:morphogenesis 212 9.78E-08
P:cell surface receptor linked signal transduction 363 2.23E-06
P:negative regulation of metabolism 107 1.02E-05
F:receptor binding 221 1.90E-05
P:cell-cell signaling 176 2.27E-05
F:cytoskeletal protein binding 137 4.97E-05
P:negative regulation of biological process 327 6.87E-05
F:ion channel activity 98 9.87E-05
C:extracellular matrix 111 0.000119
C:actin cytoskeleton 85 0.000164
P:cell differentiation 173 0.000179
P:cell adhesion 242 0.000182
P:cellular morphogenesis 111 0.000607
F:ion transporter activity 237 0.001493
P:protein amino acid phosphorylation 213 0.001593
P:ion transport 239 0.001825
F:protein kinase activity 220 0.002033
P:intracellular signaling cascade 431 0.006872
P:chromosome organization and biogenesis 105 0.007832
C:plasma membrane 608 0.008026