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Table 3 GO categories with high protein conservation. Terms of biological process are labeled as P, cellular component as C, molecular function as F.

From: Weak correlation between sequence conservation in promoter regions and in protein-coding regions of human-mouse orthologous gene pairs

GO term Number of genes P-value
F:GTPase activity 88 0
F:GTP binding 160 0
P:intracellular transport 350 0
P:small GTPase mediated signal transduction 126 1.11E-16
F:RNA binding 290 1.33E-15
C:cytosol 171 3.70E-11
P:RNA processing 198 3.25E-10
C:Golgi apparatus 216 5.63E-10
P:intracellular signaling cascade 431 2.57E-09
C:spliceosome complex 37 6.46E-09
P:transcription 640 1.76E-08
P:regulation of transcription 602 2.02E-08
F:ATP binding 520 2.85E-08
C:actin cytoskeleton 85 5.37E-08
P:vesicle-mediated transport 190 7.02E-08
P:cytoskeleton organization and biogenesis 155 9.26E-08
F:cytoskeletal protein binding 137 1.44E-07
P:secretory pathway 102 7.91E-07
C:nucleoplasm 107 1.22E-06
C:ribosome 114 1.36E-06
P:protein biosynthesis 283 1.56E-06
P:ubiquitin cycle 235 2.86E-06
F:ion channel activity 98 7.08E-05
P:protein amino acid phosphorylation 213 0.000101
F:ATPase activity 130 0.000143
C:endomembrane system 163 0.000154
F:protein kinase activity 220 0.000178
P:nervous system development 154 0.000293
F:transcription factor activity 263 0.000465
C:microtubule cytoskeleton 115 0.000595
C:vesicle 86 0.000732
F:structural molecule activity 307 0.000801
F:structural constituent of ribosome 130 0.000843
F:ubiquitin-protein ligase activity 144 0.001969
C:organelle membrane 242 0.004122
P:cell cycle 340 0.006445