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Table 4 GO categories with low protein conservation. Terms of biological process are labeled as P, cellular component as C, molecular function as F.

From: Weak correlation between sequence conservation in promoter regions and in protein-coding regions of human-mouse orthologous gene pairs

GO term

Number of genes

P-value

P:response to biotic stimulus

318

4.08E-49

P:immune response

270

1.16E-44

C:extracellular space

179

3.49E-37

P:response to stress

446

5.05E-26

F:oxidoreductase activity

309

2.35E-12

F:receptor activity

391

1.11E-11

F:receptor binding

221

2.15E-11

P:lipid metabolism

260

5.95E-11

P:electron transport

151

7.64E-10

C:lysosome

77

6.38E-08

F:peptidase activity

227

6.15E-07

P:cell proliferation

258

1.65E-06

P:cell adhesion

242

2.16E-06

C:mitochondrion

398

3.00E-05

P:proteolysis

259

4.53E-05

C:extracellular matrix

111

5.52E-05

C:peroxisome

49

8.02E-05

F:nuclease activity

60

8.50E-05

C:plasma membrane

608

0.000291

P:apoptosis

244

0.001373

P:carboxylic acid metabolism

225

0.002527

P:response to abiotic stimulus

148

0.004444

P:positive regulation of biological process

275

0.004599

P:response to chemical stimulus

129

0.004626

P:lipid biosynthesis

101

0.005576

P:cell-cell signaling

176

0.006021

P:sensory perception

111

0.008042