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Table 4 GO categories with low protein conservation. Terms of biological process are labeled as P, cellular component as C, molecular function as F.

From: Weak correlation between sequence conservation in promoter regions and in protein-coding regions of human-mouse orthologous gene pairs

GO term Number of genes P-value
P:response to biotic stimulus 318 4.08E-49
P:immune response 270 1.16E-44
C:extracellular space 179 3.49E-37
P:response to stress 446 5.05E-26
F:oxidoreductase activity 309 2.35E-12
F:receptor activity 391 1.11E-11
F:receptor binding 221 2.15E-11
P:lipid metabolism 260 5.95E-11
P:electron transport 151 7.64E-10
C:lysosome 77 6.38E-08
F:peptidase activity 227 6.15E-07
P:cell proliferation 258 1.65E-06
P:cell adhesion 242 2.16E-06
C:mitochondrion 398 3.00E-05
P:proteolysis 259 4.53E-05
C:extracellular matrix 111 5.52E-05
C:peroxisome 49 8.02E-05
F:nuclease activity 60 8.50E-05
C:plasma membrane 608 0.000291
P:apoptosis 244 0.001373
P:carboxylic acid metabolism 225 0.002527
P:response to abiotic stimulus 148 0.004444
P:positive regulation of biological process 275 0.004599
P:response to chemical stimulus 129 0.004626
P:lipid biosynthesis 101 0.005576
P:cell-cell signaling 176 0.006021
P:sensory perception 111 0.008042