Table 3 Differentially expressed genes between sexes at FDR < 0.05
Gene | Symbol | Probe | z-score | Function, GO-process |
|---|---|---|---|---|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked | DDX3Y | Ssc.7473.1.A1_at | 20.96 | Nucleoside-triphosphatase activity |
Eukaryotic translation initiation factor 2, subunit 3 gamma, | EIF2S3 | Ssc.16426.1.S1_at | 20.19 | Protein metabolism/translation regulator activity |
FAM5C – family with sequence similarity 5, member C | FAM5C | Ssc.6667.1.A1_at | -18.80 | Unknown |
Eukaryotic translation initiation factor 1A, Y-linked | EIF1AY | Ssc.26799.1.S1_at | 18.77 | Translational initiation/translation regulator activity |
DENN/MADD domain containing 4A | DENND4A | Ssc.13426.1.A1_at | -18.07 | Regulation of transcription, DNA-dependent |
Protein tyrosine phosphatase, receptor type, M | PTPRM | Ssc.31029.1.A1_at | -16.39 | Protein amino acid dephosphorylation/protein tyrosine phosphatase activity |
Latrophilin 2 | LPHN2 | Ssc.21512.1.A1_at | -15.40 | Neuropeptide signaling pathway/signal transducer activity |
Homeodomain interacting protein kinase 2 | HIPK2 | Ssc.2434.1.A1_at | -14.25 | Positive regulation of programmed cell death/transcription regulator activity |
Circadian locomoter output cycles kaput; clock homolog | CLOCK | Ssc.4897.1.A1_at | -14.10 | Circadian rhythm/transcription regulator activity |
Thymosin, beta 4, X-linked | TMSB4X | Ssc.27304.1.S1_at | 12.26 | Cytoskeleton organization and biogenesis/actin binding |
Ubiquitously transcribed tetratricopeptide repeat gene, Y-linked | UTY | Ssc.27236.1.S1_at | 11.10 | Unknown. Positive regulation of growth rate (C. elegans) |
Jumonji, AT rich interactive domain 1C | JARID1C | Ssc.21814.1.S1_at | 8.41 | Regulation of transcription, DNA-dependent/oxidoreductase activity |
Ubiquitously transcribed tetratricopeptide repeat, X chromosome | UTX | Ssc.15821.1.S1_at | 7.45 | Unknown. Positive regulation of growth rate (C. elegans) |
Glutathione S-transferase A1 | GSTA1 | Ssc.16377.1.A1_at | 6.67 | Glutathione metabolism/transferase activity |
Major histocompatibility complex, class I, A | HLA-A | Ssc.13780.11.S1_x_at | 4.81 | Antigen processing, endogenous antigen via MHC class I/MHC class I receptor activity |
Major histocompatibility complex, class I, B | HLA-B | Ssc.18552.1.S1_at | 4.39 | Antigen processing, endogenous antigen via MHC class I/MHC class I receptor activity |
Major histocompatibility complex, class I, B | HLA-B | Ssc.18554.1.S1_x_at | -4.38 | Antigen processing, endogenous antigen via MHC class I/ |
Zinc finger protein, X-linked | ZFX | Ssc.26228.1.S1_at | 4.19 | Regulation of transcription/transcriptional activator activity |
Hypothetical protein FLJ20035 | Q8IY21 | Ssc.18924.1.A1_at | -3.95 | Unknown |