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Table 4 Differentially expressed genes between breeds at FDR < 0.05

From: Transcriptome architecture across tissues in the pig

Gene

Symbol

Probe

z-score

Function, GO-process

Prostaglandin E synthase 2

PTGS2

Ssc.25850.1.A1_at

10.20

Regulation of inflammatory response/prostaglandin-endoperoxide synthase activity

Hypothetical protein DKFZp313A2432

Q8NHG7

Ssc.29609.2.A1_at

- 9.11

Unknown

ATPase, H+ transporting, lysosomal 31 kDa, V1 subunit E1

ATP6V1G2

Ssc.12005.1.A1_at

8.97

Purine ribonucleotide metabolism/ion transporter activity

Synovial sarcoma, X breakpoint 2 interacting protein

SSX2IP

Ssc.28283.1.A1_at

8.89

Cell adhesion

Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

SEMA3A

Ssc.29388.1.A1_at

7.74

Cell differentiation (nervous system development)

DIDO1 death inducer-obliterator 1

DATF1

Ssc.14412.1.A1_at

7.46

Apoptosis (M. musculus)/regulation of transcription, DNA-dependent

Hypothetical protein DKFZp313A2432

Q8NHG7

Ssc.29609.1.S1_at

- 7.18

Unknown

Immunoglobulin heavy constant mu

IGHM

Ssc.7706.1.A1_at

7.09

Response to biotic stimulus/signal transducer activity

Major histocompatibility complex, class I, B

HLA-B

Ssc.18554.1.S1_x_at

- 6.61

Antigen processing, endogenous antigen via MHC class I/MHC class I receptor activity

Armadillo repeat containing, X-linked 1

ARMCX1

Ssc.5616.1.S1_at

- 6.42

Cellular component

Tousled-like kinase 2

TLK2

Ssc.30422.1.A1_at

6.36

Establishment and/or maintenance of chromatin architecture/transferase activity, transferring phosphorus-containing groups

Follistatin-like 4

FSTL4

Ssc.11743.1.S1_at

- 6.15

Calcium ion binding

Hypothetical protein

Q8N5E3

Ssc.1256.1.A1_at

- 6.03

Unknwon

Transcription factor CP2

TFCP2

Ssc.7954.1.A1_at

- 5.83

Regulation of nucleic acid metabolism/transcription regulator activity

Major histocompatibility complex, class I, A

HLA-A

Ssc.13780.11.S1_x_at

- 5.60

Antigen processing, endogenous antigen via MHC class I/MHC class I receptor activity

Golgi phosphoprotein 4

GOLPH4

Ssc.25176.1.A1_at

- 5.12

Cellular component

Enoyl Coenzyme A hydratase domain containing 1

ECHDC1

Ssc.1146.1.S1_at

4.86

Metabolism/catalytic activity

Glycoprotein M6B

GPM6B

Ssc.8133.1.A1_at

4.85

Cell differentiation (nervous system development)/molecular function unknown

Hypothetical protein

C21orf88

Ssc.22421.1.A1_at

- 4.68

Unknwon

Polo-like kinase 2

PLK2

Ssc.29934.1.A1_at

- 4.67

Positive regulation of signal transduction/transferase activity, transferring phosphorus-containing groups

Hypothetical protein

Q9NV98

Ssc.5839.2.A1_at

- 4.67

Unknwon

Lysozyme

LYZ

Ssc.670.1.S1_at

- 4.58

Cellular catabolism (cell death)/hydrolase activity, acting on glycosyl bonds

RAB18, member RAS oncogene family

RAB18

Ssc.30567.1.A1_at

- 4.56

Endocytosis/pyrophosphatase activity

Zinc finger protein 12

ZNF12

Ssc.10665.1.A1_at

- 4.56

Regulation of cellular process/zinc ion binding

Splicing factor, arginine/serine-rich 2, interacting protein

SFRS2IP

Ssc.12708.1.A1_at

- 4.50

mRNA processing

Immunoglobulin heavy constant mu

IGHM

Ssc.11070.1.S1_at

- 4.46

Response to biotic stimulus/signal transducer activity

Synapsin III

SYN3

Ssc.3880.1.S1_at

-4.43

Regulation of neurotransmitter levels (transmission of nerve impulse)/purine nucleotide binding

Deleted in liver cancer 1

DLC1

Ssc.18150.1.A1_at

- 4.40

Negative regulation of growth/enzyme regulator activity

DEAD (Asp-Glu-Ala-Asp) box polypeptide 17

DDX17

Ssc.8674.1.A1_at

4.24

Nucleobase, nucleoside, nucleotide and nucleic acid metabolism/nucleoside-triphosphatase activity

Potassium channel modulatory factor 1

KCMF1

Ssc.25963.1.A1_at

4.16

Channel or pore class transporter activity

Mitochondrial carrier homolog 2

MTCH2

Ssc.6054.2.S1_at

- 4.12

Transport

Cytoskeleton-associated protein 4

CKAP4

Ssc.2147.2.A1_at

4.09

Cellular component

Blood vessel epicardial substance

BVES

Ssc.15540.1.A1_at

- 3.82

Muscle development

  1. z – scores correspond to Large White minus Iberian contrasts.