Skip to main content

Table 6 Prediction accuracy of the 11823860_ST2 gene set in external validation

From: A gene sets approach for identifying prognostic gene signatures for outcome prediction

training

testing

*GTG

GTP

PTG

PTP

**accuracy

sensitivity

specificity

Bild

Miller

128

49

17

19

0.6901

0.7232

0.5278

Bild

Pawitan

89

41

7

15

0.6842

0.6846

0.6818

Bild

Sotiriou_2

85

32

11

17

0.7034

0.7265

0.6071

Bild

Van de Vijver

165

67

11

37

0.7214

0.7112

0.7708

Bild

Wang

128

55

42

51

0.6486

0.6995

0.5484

Miller

Bild

37

24

17

17

0.5684

0.6066

0.5

Miller

Pawitan

84

46

6

16

0.6579

0.6462

0.7273

Miller

Sotiriou_2

77

40

7

21

0.6759

0.6581

0.75

Miller

Van de Vijver

165

67

11

37

0.7214

0.7112

0.7708

Miller

Wang

125

58

42

51

0.6377

0.6831

0.5484

Pawitan

Bild

43

18

19

15

0.6105

0.7049

0.4412

Pawitan

Miller

133

44

19

17

0.7042

0.7514

0.4722

Pawitan

Sotiriou_2

87

30

11

17

0.7172

0.7436

0.6071

Pawitan

Van de Vijver

173

59

12

36

0.7464

0.7457

0.75

Pawitan

Wang

135

48

51

42

0.6413

0.7377

0.4516

Sotiriou_2

Bild

38

23

18

16

0.5684

0.623

0.4706

Sotiriou_2

Miller

129

48

19

17

0.6854

0.7288

0.4722

Sotiriou_2

Pawitan

86

44

10

12

0.6447

0.6615

0.5455

Sotiriou_2

Van de Vijver

164

68

12

36

0.7143

0.7069

0.75

Sotiriou_2

Wang

131

52

43

50

0.6558

0.7158

0.5376

Van de Vijver

Bild

41

20

21

13

0.5684

0.6721

0.3824

Van de Vijver

Miller

136

41

21

15

0.7089

0.7684

0.4167

Van de Vijver

Pawitan

99

31

12

10

0.7171

0.7615

0.4545

Van de Vijver

Sotiriou_2

88

29

15

13

0.6966

0.7521

0.4643

Van de Vijver

Wang

141

42

54

39

0.6522

0.7705

0.4194

Wang

Bild

34

27

16

18

0.5474

0.5574

0.5294

Wang

Miller

123

54

14

22

0.6808

0.6949

0.6111

Wang

Pawitan

81

49

6

16

0.6382

0.6231

0.7273

Wang

Sotiriou_2

76

41

7

21

0.669

0.6496

0.75

Wang

Van de Vijver

154

78

8

40

0.6929

0.6638

0.8333

Total

 

3175

1325

559

746

0.6755

0.7056

0.5716

  1. *GTG – Good prognosis group predicted as Good; GTP – Good prognosis group predicted as Poor; PTG – Poor prognosis group predicted as Good; PTP – Poor prognosis group predicted as poor
  2. **accuracy = (GTG+PTP)/(GTG+GTP+PTG+PTP); sensitivity = GTG/(GTG+GTP); specificity = PTP/(PTG+PTP)