Figure 3

TFBS enriched in OXPHOS gene promoters. All genes, whose promoters were analyzed, were ordered by Pearson's correlation similarity to the expression pattern of an 'artificial gene' (the median of the expression pattern of OXPHOS genes) (see methods). Each gene was annotated for the presence of a particular TFBS in its promoter (black horizontal lines). A nonparametric statistics test was used to test if genes that contained a particular TFBS in their promoter ranked higher in the list. Statistical significance (p < 0.05) of each TFBS family is shown at the bottom (marked as significant or not significant). Statistical significance suggests an association between that TFBS and OXPHOS expression pattern. Human (top) and mouse (bottom) GNF datasets were used.