| |
Tissue M
|
Tissue N
|
Pooled
|
|---|
|
exons
|
+D
|
-D
|
+D
|
-D
|
+D
|
-D
|
|---|
|
+U
|
9
|
81
|
9
|
1
|
18
|
82
|
|
-U
|
1
|
9
|
81
|
9
|
82
|
18
|
- * +/- means the upstream (U) or downstream (D) exon in a pair is included/excluded in the transcript. In tissue M, the inclusion levels are 0.9 for U and 0.1 for D. In tissue N, the levels in 0.1 for U and 0.9 for D. The correlation coefficients between U and D are 0 in both M and N. But in pooled observation, the data show a strong negative correlation (-0.64). The cause of correlation in pooled data is not by the direct interaction between the two exons but the tissue-specific regulation.
