Table 2 Genes more highly expressed in large intestines of GF mice than those in SPF mice
Probe Set ID | Gene Name | Gene Symbol | Fold change* | p-value |
|---|---|---|---|---|
Type 1 interferon-related genes | ||||
104750_at | interferon gamma inducible protein 47 | Ifi47 | 5.13 | 0.003 |
103639_at | interferon-induced protein with tetratricopeptide repeats 2 | Ifit2 | 4.87 | 0.009 |
102906_at | T-cell specific GTPase | Tgtp | 3.99 | 0.036 |
100981_at | interferon-induced protein with tetratricopeptide repeats 1 | Ifit1 | 3.81 | 0.013 |
103202_at | guanylate nucleotide binding protein 4 | Gbp4 | 3.76 | 0.030 |
104177_at | radical S-adenosyl methionine domain containing 2 | Rsad2 | 3.20 | 0.006 |
97409_at | immunity-related GTPase family, M | Irgm | 3.03 | 0.008 |
101465_at | signal transducer and activator of transcription 1 | Stat1 | 2.63 | 0.025 |
104669_at | interferon regulatory factor 7 | Irf7 | 2.58 | 0.022 |
103335_at | lectin, galactose binding, soluble 9 | Lgals9 | 2.26 | 0.042 |
104597_at | guanylate nucleotide binding protein 2 | Gbp2 | 2.15 | 0.035 |
Immunoglobulins | ||||
96969_at | similar to Ig V-K167 precursor | LOC381776 | 7.39 | 0.014 |
93904_f_at | similar to Ig H-chain (VDJ-region) precursor | LOC238418 | 6.11 | 0.023 |
101320_f_at | similar to IgM(b) heavy pre-chain (AA -18 to 119)/similar to anti-poly(dC) monoclonal antibody heavy chain/similar to immunoglobulin heavy chain/similar to Ig heavy chain V region 3 precursor/similar to monoclonal antibody heavy chain | V165-D-J-C mu etc | 3.87 | 0.006 |
93584_at | immunoglobulin heavy chain 6 (heavy chain of IgM)/Unknown (protein for MGC:60843) | Igh-6/MGC60843 | 2.57 | 0.041 |
97575_f_at | Immunoglobulin heavy chain 1a (serum IgG2a), mRNA (cDNA clone MGC:6529 IMAGE:2651493) | Igh-VJ558 | 2.33 | 0.011 |
93638_s_at | immunoglobulin lambda chain, variable 1 | Igl-V1 | 2.25 | 0.017 |
Other molecules | ||||
103957_at | transferrin receptor | Tfrc | 6.84 | 0.001 |
160986_r_at | angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 | Ace2 | 5.13 | 0.040 |
92699_at | solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 | Slc7a9 | 4.45 | 0.014 |
96792_at | apolipoprotein B | Apob | 3.60 | 0.022 |
160933_at | interferon gamma induced GTPase | Igtp | 3.39 | 0.003 |
94936_at | meprin 1 beta | Mep1b | 3.33 | 0.011 |
96912_s_at | cytotoxic T lymphocyte-associated protein 2 alpha/cytotoxic T lymphocyte-associated protein 2 beta | Ctla2a/Ctla2b | 3.30 | 0.000 |
102373_at | glutamyl aminopeptidase | Enpep | 3.13 | 0.008 |
100030_at | uridine phosphorylase 1 | Upp1 | 3.10 | 0.006 |
98994_at | solute carrier family 34 (sodium phosphate), member 2 | Slc34a2 | 3.05 | 0.012 |
98410_at | interferon inducible GTPase 2 | Iigp2 | 2.91 | 0.007 |
92689_at | interleukin 18 binding protein | Il18bp | 2.82 | 0.021 |
103025_at | Moloney leukemia virus 10 | Mov10 | 2.79 | 0.035 |
97950_at | xanthine dehydrogenase | Xdh | 2.74 | 0.016 |
102559_at | bone morphogenetic protein 2 | Bmp2 | 2.49 | 0.020 |
96764_at | interferon inducible GTPase 1 | Iigp1 | 2.48 | 0.001 |
94088_at | polypyrimidine tract binding protein 2 | Ptbp2 | 2.42 | 0.012 |
97500_g_at | four and a half LIM domains 1 | Fhl1 | 2.32 | 0.049 |
98958_at | enhancer of yellow 2 homolog (Drosophila) | Eny2 | 2.30 | 0.021 |
103250_at | deafness, autosomal dominant 5 homolog (human) | Dfna5h | 2.26 | 0.042 |
97994_at | transcription factor 7, T-cell specific | Tcf7 | 2.25 | 0.026 |
92877_at | transforming growth factor, beta induced | Tgfbi | 2.23 | 0.023 |
102965_at | expressed sequence AI481105 | AI481105 | 2.17 | 0.019 |
104606_at | CD52 antigen | Cd52 | 2.15 | 0.004 |
99463_at | cytochrome P450, family 3, subfamily a, polypeptide 13 | Cyp3a13 | 2.14 | 0.011 |
99993_at | alanyl (membrane) aminopeptidase | Anpep | 2.08 | 0.017 |