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Figure 7 | BMC Genomics

Figure 7

From: Comparative analysis of sequence features involved in the recognition of tandem splice sites

Figure 7

Sequence conservation and splicing regulatory elements of A5EΔ4, A3EΔ3, and SEs of orthologous human and mouse genes. Upper panels A) and B) show for different AS types graphs of the mean exon conservation and of the mean conservation of exon-flanking sequences up to 100 nucleotides downstream, respectively. The conservation is shown individually for PΔ4 (panel A, green) and DΔ4 (panel B, blue) splicing exons; extension regions of A5EΔ4 splicing exons were excluded. Lower panels C) and D) show plots of occurrences of different splicing regulatory elements, located within the first 200 nucleotides of exon-flanking sequences that share > 80% exon identity and splice site signals with mouse exons.

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