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Table 1 Top five Gene Ontology (GO) slim terms of BV paralogous genes

From: Expansion of signaling genes for adaptive immune system evolution in early vertebrates

GO ID

GO term

Observed number of BV paralogous genes (%)

P value*

GO:0050789

regulation of biological process

698 (25% = 698/2842)

4.05 × 10-14

GO:0007165

signal transduction

634 (22% = 634/2842)

9.52 × 10-24

GO:0007275

multicellular organismal development

397 (14% = 397/2842)

1.59 × 10-24

GO:0006350

transcription

388 (14% = 388/2842)

4.49 × 10-10

GO:0006464

protein modification process

326 (11% = 326/2842)

1.65 × 10-27

  1. * P values are calculated by using hypergeometric distribution.
  2. A BV paralogous gene is a paralogous gene that was formed at the Base of the Vertebrate lineage.