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Table 1 Top five Gene Ontology (GO) slim terms of BV paralogous genes

From: Expansion of signaling genes for adaptive immune system evolution in early vertebrates

GO ID GO term Observed number of BV paralogous genes (%) P value*
GO:0050789 regulation of biological process 698 (25% = 698/2842) 4.05 × 10-14
GO:0007165 signal transduction 634 (22% = 634/2842) 9.52 × 10-24
GO:0007275 multicellular organismal development 397 (14% = 397/2842) 1.59 × 10-24
GO:0006350 transcription 388 (14% = 388/2842) 4.49 × 10-10
GO:0006464 protein modification process 326 (11% = 326/2842) 1.65 × 10-27
  1. * P values are calculated by using hypergeometric distribution.
  2. A BV paralogous gene is a paralogous gene that was formed at the Base of the Vertebrate lineage.